179260-79-8Relevant academic research and scientific papers
CERTAIN AMINOMETHYL BIPHENYL, AMINOMETHYL PHENYL PYRIDINE AND AMINOMETHYL PHENYL PYRIMIDINE DERIVATIVES; NOVEL DOPAMINE RECEPTOR SUBTYPE SELECTIVE LIGANDS
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, (2008/06/13)
Disclosed are compounds of the formula: STR1 where S and V are various organic or inorganic substituents;G and K are the same or different and represent N or CR' where R' is an organic or inorganic substituent;R is hydrogen or an alkyl group; R 1, X, Y, Z and T are organic or inorganic substituents; andR 2 and R 3 represent hydrogen or organic substituents; orNR 2 R 3 together represents a heterocyclic ring system;and the pharmaceutically acceptable salts thereof; which are highly selective partial agonists or antagonists at brain dopamine receptor subtypes and, thus, are useful in the diagnosis and treatment of affective disorders such as schizophrenia and depression as well as certain movement disorders such as Parkinsonism.
