179314-49-9Relevant academic research and scientific papers
Copper-Catalyzed Regioselective Ring-Opening Hydroamination of Methylenecyclopropanes
Nishikawa, Daiki,Sakae, Ryosuke,Miki, Yuya,Hirano, Koji,Miura, Masahiro
, p. 12128 - 12134 (2016/12/23)
A copper-catalyzed ring-opening hydroamination of methylenecyclopropanes with polymethylhydrosiloxane and O-benzoylhydroxylamines has been developed. The cyclopropane C-C bond cleavage occurs selectively at the more congested proximal position, and the corresponding homoallylamines are obtained in good to excellent yields. The umpolung electrophilic amination strategy with the hydroxylamine derivatives can provide a new reaction mode of methylenecyclopropanes in the catalytic hydroamination reaction.
Electrochemical allylation reactions of simple imines in aqueous solution mediated by nanoscale zinc architectures
Huang, Jing-Mei,Wang, Xu-Xiao,Dong, Yi
experimental part, p. 924 - 927 (2011/03/20)
I zinc we're alone now: The title reactions were achieved in an undivided cell fitted with a pair of zinc electrodes in aqueous solution. A preliminary study on the relationship of reaction activity and surface morphology showed that the deposited zinc powders with nanoscale architectures had very high activity.
Preparation and reactions of masked allylic organozinc reagents
Jones, Philip,Knochel, Paul
, p. 186 - 195 (2007/10/03)
Allylic zinc reagents have been prepared from sterically hindered homoallylic alcohols 10 and 13, using a novel fragmentation reaction of the corresponding zinc alkoxide, without any homocoupling products. These allylic zinc reagents react with a range of electrophiles in good to excellent yields. Substituted allylic zinc reagents have also been prepared in this manner. α-Substituted homoallylic alcohols 37, 46, and 51 give solely α- substituted products after the fragmentation-allylation sequence; these products are obtained not only regioselectively but also with extremely high anti diastereoselectivity. Likewise, γ-substituted homoallylic alcohols 57 and 58, undergo the fragmentation-allylation reaction to give γ-substituted products. The reaction has also been demonstrated to be catalytic in zinc salts.
Masked allylic zinc reagents
Jones, Philip,Millot, Nicolas,Knochel, Paul
, p. 2405 - 2406 (2007/10/03)
The preparation of allylic zinc reagents using the fragmentation of sterically hindered tertiary homoallylic alcohols is described.
Allylation of imines with samarium/allyl bromide system
Wang, Junquan,Zhang, Yongmin,Bao, Weiliang
, p. 2473 - 2477 (2007/10/03)
Imines can be readily allylated with samarium/allyl bromide system to afford homoallylamines in satisfactory yields in THF under mild conditions.
