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179334-20-4

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179334-20-4 Usage

Description

4-(4-BROMOBENZENESULFONYL)PIPERAZINE is an organic chemical compound characterized by a piperazine ring with a 4-bromobenzenesulfonyl (or p-toluenesulfon) group attached at the 4-position. It is recognized for its potential as a versatile intermediate in the synthesis of pharmaceuticals and agrochemicals, as well as its utility in the preparation of various bioactive molecules and coordination chemistry as a ligand. Furthermore, it has promising applications in materials science, particularly in the development of polymers and advanced materials.

Uses

Used in Pharmaceutical and Agrochemical Industries:
4-(4-BROMOBENZENESULFONYL)PIPERAZINE is used as a building block for the synthesis of various pharmaceuticals and agrochemicals, leveraging its versatile intermediate properties to contribute to the development of new and improved compounds.
Used in Bioactive Molecule Preparation:
4-(4-BROMOBENZENESULFONYL)PIPERAZINE is used as a reactant in the preparation of bioactive molecules, playing a crucial role in the creation of substances with potential therapeutic or biological activity.
Used in Coordination Chemistry:
4-(4-BROMOBENZENESULFONYL)PIPERAZINE is used as a ligand in coordination chemistry, enabling the formation of coordination compounds that can have specific properties and applications in various fields.
Used in Materials Science:
4-(4-BROMOBENZENESULFONYL)PIPERAZINE is used in the field of materials science for the development of polymers and advanced materials, where its unique structure and properties can contribute to the creation of innovative materials with enhanced performance characteristics.

Check Digit Verification of cas no

The CAS Registry Mumber 179334-20-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,9,3,3 and 4 respectively; the second part has 2 digits, 2 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 179334-20:
(8*1)+(7*7)+(6*9)+(5*3)+(4*3)+(3*4)+(2*2)+(1*0)=154
154 % 10 = 4
So 179334-20-4 is a valid CAS Registry Number.

179334-20-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-(4-Bromophenylsulfonyl)piperazine

1.2 Other means of identification

Product number -
Other names 1-(4-bromophenyl)sulfonylpiperazine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:179334-20-4 SDS

179334-20-4Relevant articles and documents

Discovery of Novel Chromone Derivatives Containing a Sulfonamide Moiety as Anti-ToCV Agents through the Tomato Chlorosis Virus Coat Protein-Oriented Screening Method

Jiang, Donghao,Chen, Jixiang,Zan, Ningning,Li, Chunyi,Hu, Deyu,Song, Baoan

, p. 12126 - 12134 (2021/10/26)

A number of novel chromone derivatives containing sulfonamide moieties were designed and synthesized, and the activity of compounds against tomato chlorosis virus (ToCV) was assessed using the ToCVCP-oriented screening method. Comparative molecular field analysis (CoMFA) and comparative molecular similarity index analysis (CoMSIA) models were established based on the dissociation constant (Kd) values of the target compounds, and compound 35 was designed and synthesized with the aid of CoMFA and CoMSIA models. The study of affinity interaction indicated that compound 35 exhibited excellent affinity with ToCVCP with a Kd value of 0.11 μM, which was better than that of the positive control agents xiangcaoliusuobingmi (0.44 μM) and ningnanmycin (0.79 μM). In addition, the in vivo inhibitory effect of compound 35 on the ToCVCP gene was evaluated by the quantitative real-time polymerase chain reaction. ToCVCP gene expression levels of the compound 35 treatment group were reduced by 67.2%, which was better than that of the positive control agent ningnanmycin (59.5%). Therefore, compound 35 can be used as a potential anti-ToCV drug in the future.

Novel benzo[ b ]thiophene derivatives as new potential antidepressants with rapid onset of action

Berrade, Luis,Aisa, Bárbara,Ramirez, María J.,Galiano, Silvia,Guccione, Salvatore,Moltzau, Lise Román,Levy, Finn Olav,Nicoletti, Ferdinando,Battaglia, Giuseppe,Molinaro, Gemma,Aldana, Ignacio,Monge, Antonio,Perez-Silanes, Silvia

, p. 3086 - 3090 (2011/07/07)

We report benzo[b]thiophene derivatives synthesized according to a dual strategy. 8j, 9c, and 9e with affinity values toward 5-HT7R and 5-HTT were selected to probe their antidepressant activity in vivo using the forced swimming text (FST). The results showed significant antidepressant activity after chronic treatment. 9c was effective in reducing the immobility time in FST even after acute treatment. These findings identify these compounds as a new class of antidepressants with a rapid onset of action.

IMIDAZOLYL-SUBSTITUTED AZABENZOPHENONE COMPOUNDS

-

Page/Page column 39, (2010/11/26)

The compounds of formula (I) in which X, Y, R1 and R2 have the meanings as given in the description are novel effective inhibitors of the inducible nitric oxide synthase.

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