179337-57-6 Usage
Uses
1-(4,5-Dihydro-2-thiazolyl)-3-azetidinethiol Hydrochloride is used as a reagent in the synthesis of Tebipenem Tetrahydrate (T012840); the active metabolite of Tebipenem Pivoxil (T012900) that shows excellent bactericidal activity against β-lactamase-nonproducing, ampicillin-resistant isolates.
Check Digit Verification of cas no
The CAS Registry Mumber 179337-57-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,9,3,3 and 7 respectively; the second part has 2 digits, 5 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 179337-57:
(8*1)+(7*7)+(6*9)+(5*3)+(4*3)+(3*7)+(2*5)+(1*7)=176
176 % 10 = 6
So 179337-57-6 is a valid CAS Registry Number.
179337-57-6Relevant articles and documents
An efficient method for the synthesis of 3-mercapto-1-(1,3-thiazolin-2-YL)Azetidine useful for the pendant moiety of oral carbapenem, L-084
Isoda, Takeshi,Tamai, Satoshi,Kumagai, Toshio,Nagao, Yoshimitsu
, p. 1821 - 1824 (2006)
An efficient method for the synthesis of 3-mercapto-1-(1,3-thiazolin-2-yl)azetidine (1) is described. This thiol synthesis was achieved in 3 steps from readily available 3-methanesulfonyloxyazetidine via key intermediates, Bunte salts (3 and 5). The final step was enabled to proceed under mild conditions using the benzylthiol-mediated cleavage of the S-S bond in the Bunte salt (3).{A figure is presented}.
