1794-90-7Relevant articles and documents
Cross-linking of starch with bifunctional precursors of nitroalkenes
Heeres, Andre,Van Doren, Henk A.,Gotlieb, Kees F.,Bleeker, Ido P.,Kellogg
, p. 191 - 201 (1998)
Granular starch was cross-linked with 1,3-di-O-acetyl-2-nitro-1,3-propanediol (1), 1,3-di-O-pivaloyl-2-nitro-1,3-propanediol (2), 2-nitro-3-O-pivaloyl-1-propene-3-ol (3), 1,3-di-O-acetyl-aci-2-nitro-1,3-propanediol (4), 1,3-di-O-pivaloyl-aci-2-nitro-1,3-propanediol (5) and 1,6-di-O-acetyl-2,5-dinitro-1,6-hexanediol (6). The bifunctional precursors for the nitro-alkenes 1, 2, 3, and 4 were readily synthesized in high yields from nitromethane, paraformaldehyde and acetic anhydride (1, 3) or pivaloyl chloride (2, 4), respectively. The reaction rate for the cross-linking was very high, and for 1 and 3, the reaction reached completion within 1 h (at room temperature). The swelling capacities of the products obtained when starch was cross-linked with precursors for the nitroalkenes 1-4 and 6 were lower in comparison to epichlorohydrin cross-linked starch. These results indicate a high reaction efficiency at low degrees of substitution. Cross-linked 2-nitroalkyl starch ethers were synthesized in a one-pot synthesis by addition of 1 or 3 and 2-nitroalkyl acetates to granular suspensions of starch. Copyright (C) 1998 Elsevier Science Ltd.
Formation and Out-of-Equilibrium, High/Low State Switching of a Nitroaldol Dynamer in Neutral Aqueous Media
Elofsson, Ulla,Karalius, Antanas,Kravchenko, Oleksandr,Ramstr?m, Olof,Szabó, Zoltán,Yan, Mingdi,Zhang, Yang
supporting information, p. 3434 - 3438 (2020/02/05)
The nitroaldol reaction is demonstrated as an efficient dynamic covalent reaction in phosphate buffers at neutral pH. Rapid equilibration was recorded with pyridine-based aldehydes, and dynamic oligomerization could be achieved, leading to nitroaldol dynamers of up to 17 repeating units. The dynamers were applied in a coherent stimuli-responsive molecular system in which larger dynamers transiently existed out-of-equilibrium in a neutral aqueous system rich in formaldehyde, controlled by nitromethane.
2-amino-1, 3-propanediol synthesis process
-
Paragraph 0006; 0017; 0018, (2019/04/06)
The invention discloses a 2-amino-1, 3-propanediol synthesis process. In a homogeneous system, nitromethane reacts with formalin in a methanol/water system by the aid of catalytic activity of organicalkali triethylamine catalysts to generate an intermediate product mainly comprising 2-nitro-1, 3-propanediol, the intermediate product is not separated in the homogeneous system, Raney nickel catalysts are directly added to perform catalytic hydrogenation reduction reaction and generate mixed mother solution taking 2-amino-1, 3-propanediol as a main product, and the mother solution is separated,concentrated, distilled, recrystallized, purified, separated and dried to obtain a finished product. Separation steps are simplified, the process is low in production equipment requirement, simple andconvenient in operation, less in wastewater discharge amount, low in cost and more suitable for industrial large-scale production and application, and the recycling rate of Raney nickels is effectively increased in the post-treatment process.
