179462-74-9

Upstream product

• 179129-03-4 (E)-3-(3,4-Dihydroxy-phenyl)-acrylic acid 1-allyloxycarbonyl-2-(3,4-dihydroxy-phenyl)-ethyl ester 
• 179128-97-3 (E)-3-(3,4-Bis-allyloxy-phenyl)-acrylic acid 1-allyloxycarbonyl-2-(3,4-bis-allyloxy-phenyl)-ethyl ester 
• 1322088-17-4 C₂₂H₂₄O₈ 
• 676626-91-8 (Z)-4-(3,4-dimethoxybenzylidene)-2-methyloxazol-5 (4H)-one 
• 120-14-9 3,4-dimethoxy-benzaldehyde 
• 1322088-12-9 (E)-1-(allyloxy)-3-(3,4-dimethoxyphenyl)-1-oxopropan-2-yl 3-(3,4-dimethoxyphenyl)acrylate 
• 1322088-10-7 allyl 3-(3,4-dimethoxyphenyl)-2-hydroxypropanoate 
• 32255-79-1 2-hydroxy-3-(3,4-dimethoxyphenyl)propanoic acid 
• 143815-52-5 (Z)-3-(3,4-dimethoxyphenyl)-2-hydroxyacrylic acid 
• 139-85-5 3,4-dihydroxybenzaldehyde 
• 179128-90-6 3-(3,4-Bis-allyloxy-phenyl)-2-hydroxy-propionic acid allyl ester 
• 179128-95-1 (E)-3-(3,4-Bis-benzyloxy-phenyl)-acrylic acid 2-(3,4-bis-benzyloxy-phenyl)-1-(2-trimethylsilanyl-ethoxycarbonyl)-ethyl ester 
• 179128-96-2 (E)-3-(3,4-Bis-benzyloxy-phenyl)-acrylic acid 1-allyloxycarbonyl-2-(3,4-bis-benzyloxy-phenyl)-ethyl ester 
• 179128-88-2 3-(3,4-Bis-benzyloxy-phenyl)-2-hydroxy-propionic acid 2-trimethylsilanyl-ethyl ester 

Downstream Products

• 303175-68-0 rosmarinyl isopropyl ester 
• 118120-95-9 rosmarinic acid, ethyl ester 
• 54910-34-8 Pentamethyl-rosmarinat 

Relevant academic research and scientific papers

Synthesis of derivatives of methyl rosmarinate and their inhibitory activities against matrix metalloproteinase-1 (MMP-1)

A series of MMP-1 inhibitors have been identified based upon a methyl rosmarinate scaffold using structure-based drug design methods. The best compound in the series showed an IC50 value of 0.4 μM. A docking study was conducted for compound (S)

Bryophyte constituents; 7: New synthesis of (+)-rosmarinic acid and related compounds

Efficient and expeditious syntheses are described for rosmarinic acid (1) and its derivatives 2-4, making extensive use of allyl protective groups for both carboxylic acids and phenolic building blocks. (+)(R)-Rosmarinic acid was obtained by a chemoenzymatic resolution of its phenyl lactic acid precursors.