1794789-93-7

Basic information

• Product Name: Vilazodone-d8
• Synonyms: Vilazodone-d8;5-[4-[4-(5-Cyano-1H-indol-3-yl)butyl]-1-(piperazinyl-d8)]-2-benzofurancarboxaMide;EMD 515259-d8
• CAS NO: 1794789-93-7
• Molecular Formula: C26H26N5O2
• Molecular Weight: 440.51694
• Product Categories: Amines;Aromatics;Heterocycles;Intermediates & Fine Chemicals;Isotope Labelled Compounds;Pharmaceuticals
• Mol File: 1794789-93-7.mol
• Article Data: 0

Chemical Properties

• Melting Point: 195-198°C
• Appearance: /
• Storage Temp.: Refrigerator
• CAS DataBase Reference: Vilazodone-d8(CAS DataBase Reference)
• NIST Chemistry Reference: Vilazodone-d8(1794789-93-7)
• EPA Substance Registry System: Vilazodone-d8(1794789-93-7)

Safety Data

• Hazardous Substances Data: 1794789-93-7(Hazardous Substances Data)

Usage

Description

Vilazodone-d8 is intended for use as an internal standard for the quantification of vilazodone by GC- or LC-MS. Vilazodone is a selective serotonin reuptake inhibitor (SSRI) and a partial agonist of the serotonin (5-HT) receptor subtype 5-HT1A (IC50s = 0.2 and 0.5 nM, respectively). It increases extracellular 5-HT in the rat ventral hippocampus and frontal cortex when administered intraperitoneally at doses of 1 and 3 mg/kg, respectively. Vilazodone (1 mg/kg, i.p.) decreases immobility in the forced swim test in both rats and mice. Formulations containing vilazodone have been used in the treatment of depression.

Uses

Different sources of media describe the Uses of 1794789-93-7 differently. You can refer to the following data:
1. (Vilazodone-d8) Labelled Vilazodone. It is a combined serotonin specific reuptake inhibitor (SSRI) and 5-HT1A receptor partial agonist currently under clinical evaluation for the treatment of major depression. Antidepressant.;Labeled Vilazodone, intended for use as an in
2. Labelled Vilazodone (V265000). It is a combined serotonin specific reuptake inhibitor (SSRI) and 5-HT1A receptor partial agonist currently under clinical evaluation for the treatment of major depression. Antidepressant.
3. Labelled Vilazodone (V265000). It is a combined serotonin specific reuptake inhibitor (SSRI) and 5-HT1A receptor partial agonist currently under clinical evaluation for the treatment of major depression.