179601-65-1

Upstream product

• 93102-05-7 N-benzyl-N-(methoxymethyl)-N-[(trimethylsilyl)methyl]amine 
• 1221289-17-3 cis-5-benzyltetrahydro-1H-furo[3,4-c]pyrrole-1,3(3aH)-dione 
• 7732-18-5 water 
• 607362-87-8 1-benzyl-pyrrolidine-3,4-dicarboxylic acid dimethyl ester 

Downstream Products

• 848616-45-5 C₆H₁₃NO₂ 
• 60889-33-0 cis‐hexahydro‐1H‐furo[3,4‐c]pyrrol‐5‐ium chloride 

Relevant academic research and scientific papers

An Approach to 3-Oxa-7-azabicyclo[33.0]octanes - Bicyclic Morpholine Surrogates

An approach to 3-oxa-7-azabicyclo[3.3.0]octanes, bicyclic morpholine analogues, is reported, which relies on [3+2] cycloaddition of maleic anhydrides or furan-2(5 H)-ones and an in situ generated azomethine ylide. The utility of the method was demonstrated on a multigram scale.

QUINOLONE ANTIBACTERIAL AGENTS

Compounds of formula I and methods for their preparation are disclosed. Further disclosed are methods of making biologically active compounds of formula I as well as pharmaceutically acceptable compositions comprising compounds of formula I. Compounds of formula I as disclosed herein can be used in a variety of applications including use as antibacterial agents.

Bicyclic oxazine and thiazine oxazolidinone antibacterials

Phenyloxazolidinone compound of formula (I)or a pharmaceutically acceptable salt thereof characterized by a bicyclic thiazine or oxazine substituent. The compounds are useful antimicrobial agents, effective against a number of human and veterinary pathogens, including gram-positive aerobic bacteria such as multiply-resistant staphylococci, streptococci and enterococci as well as anaerobic organisms such as Bacteroides spp. and Clostridia spp. species, and acid-fast organisms such as Mycobacterium tuberculosis, Mycobacterium avium and Mycobacterium spp.