179613-04-8Relevant articles and documents
Chiral: N, N ′-dioxide-iron(iii)-catalyzed asymmetric sulfoxidation with hydrogen peroxide
Dong, Shunxi,Feng, Lili,Feng, Xiaoming,Liu, Xiaohua,Wang, Fang
, p. 3233 - 3236 (2020)
A highly enantioselective sulfoxidation of various sulfides has been achieved by a N,N′-dioxide-iron(iii) complex with 35% aq. H2O2 as the oxidant. The utility of the current method was demonstrated by asymmetric gram-scale synthesis of drug molecule (R)-modafinil. Moreover, a possible working mode was provided to elucidate the chiral induction.