17965-72-9

Usage

Uses

Used in Pharmaceutical Industry:
3,7-Dibromo-1,5-naphthyridine is used as a key intermediate in the synthesis of various pharmaceuticals for its ability to create a wide range of functionalized naphthyridine derivatives with diverse applications. Its high reactivity allows for the development of new drugs with potential therapeutic uses.
Used in Agrochemical Industry:
3,7-Dibromo-1,5-naphthyridine is used as a starting material in the synthesis of agrochemicals, contributing to the development of novel compounds with potential applications in agriculture. Its versatility in chemical reactions enables the creation of new agrochemicals with improved properties and effectiveness.
Used in Organic Synthesis:
3,7-Dibromo-1,5-naphthyridine is used as a valuable building block in organic synthesis for its ability to participate in a variety of chemical reactions. This allows chemists to create new functionalized naphthyridine derivatives with potential applications in various fields, including pharmaceuticals, agrochemicals, and other industries.

Upstream product

• 254-79-5 1,5-naphthyridine 

Relevant academic research and scientific papers

Synthetic method of 7-bromo-1,5-naphthyridine-3-methanoic acid

The invention provides a synthetic method of 7-bromo-1,5-naphthyridine-3-methanoic acid. The synthetic method of the 2-bromo-1,5-naphthyridine-3-methanoic acid comprises the steps of taking 1,5-naphthyridine as a raw material and reacting to generate 7-bromo-1,5-naphthyridine-3-methyl pyrazinecarboxylate; and finally hydrolyzing the 7-bromo-1,5-naphthyridine-3-methyl pyrazinecarboxylate under thealkaline condition to generate the 7-bromo-1,5-naphthyridine-3-methanoic acid. According to the synthetic method of the 7-bromo-1,5-naphthyridine-3-methanoic acid, a synthetic route which takes 1,5-naphthyridine as a raw material is provided. The synthetic method of the 7-bromo-1,5-naphthyridine-3-methanoic acid has the advantages that the synthetic route is simple, the raw materials are low in cost, are simple and are easily obtained, aftertreatment is facilitated, the success rate is high, the synthetic route is easy to enlarge and the like.

SUBSTITUTED NAPHTHYRIDINE AND QUINOLINE COMPOUNDS AS MAO INHIBITORS

The invention provides a chemical entity of Formula (I) wherein R1, R2, R3, Y, and n have any of the values described herein and compositions comprising such chemical entities; methods of making them; and their use in a wi

Synthesis and SAR comparison of regioisomeric aryl naphthyridines as potent mGlu5 receptor antagonists

We describe three novel regioisomeric series of aryl naphthyridine analogs, which are potent antagonists of the Class III GPCR mGlu5 receptor. The synthesis and in vitro and in vivo pharmacological activities of these analogs are discussed.