179691-39-5

Basic information

• Product Name: Thymidine, 5'-[2-(2-chloro-6-nitrophenyl)ethyl carbonate]
• CAS NO: 179691-39-5
• Molecular Formula: C19H20ClN3O9
• Molecular Weight: 469.835
• Mol File: 179691-39-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Thymidine, 5'-[2-(2-chloro-6-nitrophenyl)ethyl carbonate](CAS DataBase Reference)
• NIST Chemistry Reference: Thymidine, 5'-[2-(2-chloro-6-nitrophenyl)ethyl carbonate](179691-39-5)
• EPA Substance Registry System: Thymidine, 5'-[2-(2-chloro-6-nitrophenyl)ethyl carbonate](179691-39-5)

Safety Data

• Hazardous Substances Data: 179691-39-5(Hazardous Substances Data)

Upstream product

• 179691-24-8 2-(2-chloro-6-nitrophenyl)ethoxycarbonyl chloride 
• 50-89-5 thymidine 
• 102493-68-5 2-(2-chloro-6-nitrophenyl)-ethanol 
• 83-42-1 6-chloro-2-nitrotoluene 

Relevant articles and documents

New photolabile protecting groups of the 2-(2- nitrophenyl)ethoxycarbonyl-and the 2-(2-nitrophenyl)ethylsulfonyl-type for the oligonucleotide synthesis

New photolabile blocking groups have been synthesized and introduced into the 5'-OH position of thymidine. The 5'-O-protected thymidines were irradiated at 365 nm under identical conditions and the half-lives and thymidine yields were determined to investigate the influence of different substituents in the two corresponding series.

New photolabile protecting groups in nucleoside and nucleotide chemistry - Synthesis, cleavage mechanisms and applications

New photolabile protecting groups have been found in the 2-(2- nitrophenyl)ethoxycarbonyl and the 2-(2-nitrophenyl)ethylsulfonyl group, respectively. The influence of substituents at the phenyl ring as well as the side-chain has been investigated regarding the photolysis rates on irradiation at 365 mn. β-Branching in the side-chain leads to highly increased rates of photodeprotection. A new type of photocleavage mechanism consisting of a photoinduced β-elimination process is proposed.