1797-87-1Relevant articles and documents
Chemoselective oxidation of 6-hydroxyalkylpteridine and its application to synthesis of 6-acyl-7,8-dihydropteridine
Landge, Sudhir S.,Kudoh, Kazunari,Yamada, Yuri,Murata, Shizuaki
, p. 911 - 918 (2008/03/13)
Alcohol-selective oxidation of 6-l′-hydroxyalkylpteridines catalyzed by ruthenium (IV), RuO4-, gives 6-acylpteridines in high yields. Partial reduction of the products affords 6-acyl-7,8-dihydropteridine derivatives, such as a lipophilic derivative of sepiapterin, deoxysepiapterin, and sepiapterin-C.
CHEMICAL SYNTHESIS OF DEOXYSEPIAPTERIN
Baur, Ralph,Sugimoto, Takashi,Pfleiderer, Wolfgang
, p. 1025 - 1028 (2007/10/02)
A chemical synthesis of the yellow eye pigment deoxysepiapterin of Drosophila melanogaster has been achieved from 7-alkylthio pteridines by homolytic nucleophilic acylation at C-6 and subsequent hydrolyses to 6-proprionylpterin derivatives followed by desulfurizations with copper-aluminium alloy.