179797-24-1

Upstream product

• 179533-23-4 (2S)-3-O-(2,2-dimethoxyethyl)-1,2-O-isopropylideneglycerol 
• 98-59-9 p-toluenesulfonyl chloride 
• 179797-21-8 methyl 3-oxa-2,3,4-trideoxy-β-D-glycero-hexopyranoside 

Relevant academic research and scientific papers

Synthesis of kanamycin A analogs containing 6-amino-3-oxa-2,3,4,6-tetradeoxy-D- and -L-glycero-hexopyranose

6-Azido-3-oxa-2,3,4,6-tetradeoxy-D- and -L-glycero-hexopyranoses were synthesized in five steps from (2S)- and (2R)-1,2-O-isopropylideneglycerols, respectively. After conversion into the corresponding ethyl 1-thioglycosides, each was condensed with a protected derivative of 6-O-(3-amino-3-deoxy-α-D-glucopyranosyl)-2-deoxystreptamine (16). Deprotection and reduction of the azido group of the condensation products gave the title compounds.