17983-33-4

Upstream product

• 4028-23-3 Allylchlorodimethylsilane 
• 106-37-6 1.4-dibromobenzene 
• 18236-77-6 (4-bromophenyl)chlorodimethylsilane 
• 106-95-6 allyl bromide 

Downstream Products

• 261761-38-0 4-(allyldimethylsilyl)benzaldehyde 
• 1178886-55-9 Si(C₆H₄Si(CH₃)2(CH₂CHCH₂))4 
• 1609152-75-1 meso-tetrakis(4-allyldimethylsilylphenyl)porphyrin 
• 261761-43-7 (Rs,S)-(-)-methyl N-(tert-butanesulfinyl)-3-amino-3-(4-allyldimethylsilyl)phenylpropanoate 
• 261761-41-5 (R)-(-)-N-[(4-allyldimethylsilylphenyl)methylene]-tert-butanesulfinamide 
• 288372-52-1 ({2-[4-(allyl-dimethyl-silanyl)-phenyl]-ethyl}-tert-butoxycarbonyl-amino)-oxo-acetic acid ethyl ester 
• 359792-69-1 (S_R,R)-(+)-methyl 3-(p-tolylsulfinamido)-3-([4-allyldimethylsilyl]phenyl)propanoate 
• 288372-40-7 {[4-(allyl-dimethyl-silanyl)-benzyl]-tert-butoxycarbonyl-amino}-oxo-acetic acid ethyl ester 
• 288372-10-1 (S)-methyl-3-([4-allyldimethylsilyl]naphthyl)-2-(tert-butoxycarbamido)propanoate 
• 288372-21-4 (S)-methyl-2-acetamido-4-([4-allyldimethylsilyl]phenyl)butanoate 
• 288372-20-3 (2Z)-methyl-2-acetamido-4-([4-allyldimethylsilyl]phenyl)but-2-enoate 
• 288372-09-8 (S)-methyl-2-acetamido-3-([4-allyldimethylsilyl]phenyl)propanoate 
• 359792-68-0 (S)-(+)-N-(4-allyldimethylsilylbenzylidene)-p-toluenesulfonamide 

Relevant academic research and scientific papers

Silicon-based aromatic transferring linkers for traceless solid-phase synthesis of aryl-, polyaryl-, and heteroaryl-containing compounds

A number of arylsilane-based linkers are prepared for traceless solid-phase synthesis. General methodologies for introduction of the silyl group and various functional groups to aromatic, polyaromatic, and heteroaromatic rings are developed. Also, broad u

Allyl-end-grafted carbosilane dendrimers based on 1,4-phenylene units: Synthesis, reactivity, structure, and bonding motifs

The synthesis of a series of carbosilanes of type 1-Br-C6H 4-4-SiMe3-n(CH2CH=CH2)n (n = 1, 2, 3), Si[C6H4-4-SiMe3-n(CH 2CH=CH2)n

Rapid, high-yield, solid-phase synthesis of the antitumor antibiotic sansalvamide a using a side-chain-tethered phenylalanine building block

(matrix presented) A 10-step solid-phase synthesis of the cytotoxic depsipeptide sansalvamide A (1) has been accomplished in an overall yield of 67% with >95% purity employing polymer-bound phenylalanine building block 2. Both the N- and C-termini of 2 are extended followed by on-resin head-to-tail macrocyclization of the linear peptide in a high yield. This should be a general stategy for the synthesis of diverse libraries of cyclic peptides and depsipeptides that contain exclusively phenylalanine and other hydrophobic side chains.

Traceless solid-phase synthesis of chiral 3-aryl beta-amino acid containing peptides using a side-chain-tethered beta-amino acid building block.

[reaction: see text] A general method for the attachment of a chiral aromatic side-chain-containing beta-amino acid to a polymer support using a traceless silyl linkage strategy has been developed. Using this building block, solid-phase synthesis was carried out to obtain tripeptide analogues with the aromatic ring either unsubstituted or halogenated (Br, I) at the position of the silyl group. The building blocks could generate libraries of peptidomimetics or cyclic peptides containing beta-amino acids with nonpolar side chains.