179895-59-1

Basic information

• Product Name: (Z)-5-(3-Fluorobenzylidene)-2,2,4-trimethyl-2,5-dihydro-1H-[1]benzopyrano[3,4-f]quinoline
• Synonyms: LG-120744
• CAS NO: 179895-59-1
• Molecular Formula: C₂₆H₂₂FNO
• Molecular Weight: 383.46974
• Mol File: 179895-59-1.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: (Z)-5-(3-Fluorobenzylidene)-2,2,4-trimethyl-2,5-dihydro-1H-[1]benzopyrano[3,4-f]quinoline(CAS DataBase Reference)
• NIST Chemistry Reference: (Z)-5-(3-Fluorobenzylidene)-2,2,4-trimethyl-2,5-dihydro-1H-[1]benzopyrano[3,4-f]quinoline(179895-59-1)
• EPA Substance Registry System: (Z)-5-(3-Fluorobenzylidene)-2,2,4-trimethyl-2,5-dihydro-1H-[1]benzopyrano[3,4-f]quinoline(179895-59-1)

Safety Data

• Hazardous Substances Data: 179895-59-1(Hazardous Substances Data)

Upstream product

• 179894-93-0 2,2,4-trimethyl-1,2-dihydro-6-oxa-1-azachrysen-5-one 
• 64168-34-9 (3-fluorobenzyl)magnesium chloride 

Relevant articles and documents

5-benzylidene 1,2-dihydrochromeno[3,4-f]quinolines, a novel class of nonsteroidal human progesterone receptor agonists

A novel series of nonsteroidal progestins, 5-benzylidene-1,2- dihydrochromeno[3,4-f]quinolines (2), was discovered, and a preliminary structure-activity relationship study around the 5-benzylidene ring generated several potent human progesterone receptor

STEROID RECEPTOR MODULATOR COMPOUNDS AND METHODS

Non-steroidal compounds which are high affinity, high selectivity modulators for steroid receptors are disclosed. Also disclosed are pharmaceutical compositions incorporating such compounds, methods for employing the disclosed compounds and compositions for treating patients requiring steroid receptor agonist or antagonist therapy, intermediates useful in the preparation of the compounds and processes for the preparation of the steroid receptor modulator compounds.

Steroid receptor modulator compounds and methods

Non-steroidal compounds which are high affinity, high selectivity modulators for steroid receptors are disclosed. Also disclosed are pharmaceutical compositions incorporating such compounds, methods for employing the disclosed compounds and compositions for treating patients requiring steroid receptor agonist or antagonist therapy, intermediates useful in the preparation of the compounds and processes for the preparation of the steroid receptor modulator compounds.