179927-40-3

Upstream product

• 1257215-02-3 (2R,3S,4R)-2,3,4-tris(benzyloxy)hex-5-en-1-yl methanesulfonate 
• 1227291-99-7 C₂₈H₃₃NO₇S 
• 179927-39-0 2,3,4-tri-O-benzyl-5-O-methanesulfonyl-D-arabinose diethyl dithioacetal 
• 108713-91-3 2,3,4-tri-O-benzyl-D-arabinose diethyl dithioacetal 

Downstream Products

• 179927-41-4 Methanesulfonic acid (E)-(2R,3S,4R)-2,3,4-tris-benzyloxy-6-(diphenoxy-phosphoryl)-hex-5-enyl ester 
• 289046-04-4 2,3,4-tri-O-benzyl-5-O-methanesulfonyl-D-arabitol 
• 179927-42-5 [(E)-(3R,4S,5S)-3,4,5-Tris-benzyloxy-6-(4-methoxy-phenyltellanyl)-hex-1-enyl]-phosphonic acid diphenyl ester 
• 289045-99-4 (phenylseleno) 2,3,4-tri-O-benzyl-5-benzylseleno-D-arabit-1-yl formate 
• 289046-00-0 2,3,4-tri-O-benzyl-5-benzylseleno-D-arabitol 

Relevant academic research and scientific papers

Straightforward synthesis of diverse 1-deoxyazapyranosides via stereocontrolled nucleophilic additions to six-membered cyclic nitrones

A systematic study of diastereoselective nucleophilic addition of Grignard reagents to six-membered chiral tri-O-benzyl cyclic nitrones is described. With all eight chiral cyclic nitrones and asymmetric reaction conditions in hand, a practical methodology is established for the preparation of diverse 1-deoxyazapyranosides bearing various stereogenic centers. We have developed practical methods to prepare all eight six-membered chiral cyclic nitrones. Using these cyclic nitrones and diastereoselective nucleophilic additions, 12 examples of diverse 1-deoxyazapyranosides including enantiomers were synthesized to demonstrate the generality and flexibility of this new approach.

A practical synthesis of sugar-derived cyclic nitrones: Powerful synthons for the synthesis of iminosugars

Sugar-derived cyclic nitrones were synthesized from the corresponding aldoses through an efficient and practical procedure involving a seven-step reaction sequence in good to excellent overall yield (10-42%). This synthetic strategy, requiring only inexpe

Exploratory experiments with aryl telluride carbohydrates. Synthesis of carbocycles using intramolecular radical cyclization

The preparation of cyclohexanoids and cyclopentanoids, potential precursors of biologically interesting molecules is described. The key step of the synthesis is an exo cyclization of 5-hexenyl or 6-heptenyl radicals. The radical, generated by radical exchange from carbohydrate anisyl tellurides (D-galactose or D-arabinose) cyclized into polyhydroxylated cyclohexane or cyclopentane derivatives.