179927-76-5Relevant academic research and scientific papers
Hydroxyl-directed reductive ring opening at the C-2 position of functionalized 2-aryloxetanes
Bach, Thorsten,Lange, Christian
, p. 4363 - 4364 (2007/10/03)
2-Aryloxetanes 3 are cleaved at the C-2 position upon treatment with lithium aluminium hydride to deliver the triols 4 in good yields (61-85 %). The regioselective ring opening at the more hindered position is facilitated by a hydoxyl group attached to the arene.
