179949-30-5

Upstream product

• 100-46-9 benzylamine 
• 503821-74-7 (4R,5S)-4-Formyl-2,2-dimethyl-5-phenyl-oxazolidine-3-carboxylic acid tert-butyl ester 
• 148903-85-9 tert-butyl (4S,5S)-4-(hydroxymethyl)-2,2-dimethyl-5-phenyl-1,3-oxazolidine-3-carboxylate 
• 28143-91-1 (1S,2S)-2-amino-1-phenyl-1,3-diol 
• 24424-99-5 di-tert-butyl dicarbonate 
• 19810-31-2 Benzyloxyacetyl chloride 

Downstream Products

• 150949-66-9 (+)-(3R,4R)-cis-1-benzyl-3-benzyloxy-4-formyl-2-azetidinone 
• 179949-34-9 (3R,4S)-4-((1S,2S)-1-Amino-2-hydroxy-2-phenyl-ethyl)-1-benzyl-3-benzyloxy-azetidin-2-one 

Relevant academic research and scientific papers

Application of (+)-(1S,2S)-2-amino-1-phenylpropan-1,3-diol in the formal total synthesis of carbapenems, novel 4-cyano-β-lactams and β-hydroxy aspartates

The imines derived from (+)-(1S,2S)-2-amino-1-phenylpropan-1,3-diol furnished cis-β-lactams stereoselectively on the Staudinger reaction. These homochiral cis-β-lactams were converted in to cis-β-lactams possessing aminol side chain at C-4. These aminols