179999-08-7Relevant academic research and scientific papers
Synthesis of 5-amino-4-sulfonamidoimidazole nucleosides as potential inhibitors of purine nucleotide biosynthesis, and of an imidazothiadiazine dioxide analogue of adenosine
Frame, A. Scott,Wightman, Richard H.,Mackenzie, Grahame
, p. 9219 - 9236 (2007/10/03)
5-Amino-4-sulfonamido-1-(β-D-ribofuranosyl)imidazole 6 and two more complex sulfonamides, one of which (8) incorporates an L-aspartyl unit, have been prepared as potential inhibitors of the intermediate stages in the pathway for de novo biosynthesis of pu
