180001-98-3 Usage
Uses
Used in Pharmaceutical Industry:
TERT-BUTYL N-[3-(ACETIMIDOYLAMINOMETHYL)BENZYL]CARBAMATE, HYDROCHLORIDE is used as an intermediate for the development of selective inducible nitric oxide synthase (iNOS) inhibitors. These inhibitors are crucial in managing conditions where excessive nitric oxide production can lead to inflammation and other health issues. Its long-acting nature and high potency make it a valuable component in the creation of effective pharmaceuticals targeting iNOS-related conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 180001-98-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,0,0,0 and 1 respectively; the second part has 2 digits, 9 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 180001-98:
(8*1)+(7*8)+(6*0)+(5*0)+(4*0)+(3*1)+(2*9)+(1*8)=93
93 % 10 = 3
So 180001-98-3 is a valid CAS Registry Number.
InChI:InChI=1/C15H23N3O2.ClH/c1-11(16)17-9-12-6-5-7-13(8-12)10-18-14(19)20-15(2,3)4;/h5-8H,9-10H2,1-4H3,(H2,16,17)(H,18,19);1H
180001-98-3Relevant academic research and scientific papers
Zhu, Yaoqiu,Nikolic, Dejan,Van Breemen, Richard B.,Silverman, Richard B.
, p. 858 - 868 (2005)
Nitric oxide synthases (NOS) are hemoproteins that catalyze the reaction of L-arginine to L-citrulline and nitric oxide. N-(3-(Aminomethyl)benzyl) acetamidine (1400W) was reported to be a slow, tight-binding, and highly selective inhibitor of iNOS in vitr
