180063-09-6Relevant articles and documents
Lipase catalyzed enantioselective transesterification of 5-Acyloxy-2(5H)-furanones
Van Der Deen, Hanneke,Hof, Robert P.,Van Oeveren, Arjan,Feringa, Ben L.,Kellogg, Richard M.
, p. 8441 - 8444 (1994)
Several lipases catalyse the transesterification of γ-acyloxyfuranones in organic solvents with high enantioselectivities. This method has been used for the kinetic resolution of 5-acetoxy-2(5H)-furanone, 5-acetoxy-4-methyl-2(5H)-furanone and 5-propionyloxy-2(5H)-furanone, in e.e.'s ranging from 68-98%.