1801262-20-3Relevant academic research and scientific papers
POSITIVE ALLOSTERIC MODULATORS OF THE MUSCARINIC ACETYLCHOLINE RECEPTOR M1
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Paragraph 0317; 0319, (2020/05/14)
Described are positive allosteric modulators of muscarinic acetylcholine receptor M1 (mAChR M1), pharmaceutical compositions including the compounds, and methods of using the compounds and compositions for treating neurological disorders, psychiatric disorders, or a combination thereof.
PHENYL-TRIAZOLO-PYRIDINE COMPOUNDS
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, (2017/02/24)
The present invention provides a compound of the Formula (I) below: wherein R1 is selected from the group consisting of H, CH3, CN, —CH2CN, —C(CH3)2CN, F, Cl, and Br; R2 is selected from the group consisting of H, —O(C1-C3alkylene)R4, —CH2CN, CN, —OCH3, CF2, —C(CH3)2CN, —C(CH3)2, —S(O)2CH3, —S(O)2NH2, and —OCF2; R3 is selected from the group consisting of H, CH3, and —OCH3; and R4 is selected from the group consisting of H, —C(CH3)2CN, —OCH3, —S(O)2CH3, CN, and —C(CH3)2OH; or a pharmaceutical salt thereof, methods of treating type two diabetes using the compound and a process for preparing the compound.
PHENYL-TRIAZOLO-PYRIDINE COMPOUNDS
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, (2015/07/23)
The present invention provides a compound of the Formula (I) below: wherein R1 is selected from the group consisting of H, CH3, CN, -CH2CN, -C(CH3)2CN, F, Cl, and Br; R2 is selected from the group consisting of H, -O(C1-C3alkylene)R4, -CH2CN, CN, - OCH3, CF2, -C(CH3)2CN, -C(CH3)2, -S(O)2CH3, -S(O)2NH2, and -OCF2; R3 is selected from the group consisting of H, CH3, and -OCH3; and R4 is selected from the group consisting of H, -C(CH3)2CN, -OCH3, -S(O)2CH3, CN, and -C(CH3)2OH; or a pharmaceutical salt thereof, methods of treating type two diabetes using the compound and a process for preparing the compound.
