180128-63-6

Basic information

• Product Name: ethyl (3-methylene-4(R)-methyl-5(R)-phenylpyrrolidinone-1-yl)-2(R)-phenylacetate
• CAS NO: 180128-63-6
• Molecular Weight: 349.43
• Mol File: 180128-63-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: ethyl (3-methylene-4(R)-methyl-5(R)-phenylpyrrolidinone-1-yl)-2(R)-phenylacetate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl (3-methylene-4(R)-methyl-5(R)-phenylpyrrolidinone-1-yl)-2(R)-phenylacetate(180128-63-6)
• EPA Substance Registry System: ethyl (3-methylene-4(R)-methyl-5(R)-phenylpyrrolidinone-1-yl)-2(R)-phenylacetate(180128-63-6)

Safety Data

• Hazardous Substances Data: 180128-63-6(Hazardous Substances Data)

Upstream product

• 142035-36-7 (R)-Phenyl-{[1-phenyl-meth-(E)-ylidene]-amino}-acetic acid ethyl ester 

Downstream Products

• 180128-65-8 (4R,5R)-4-Methyl-3-methylene-5-phenyl-1-(1-phenyl-vinyl)-pyrrolidin-2-one 
• 180128-64-7 (3-methylene-4(R)-methyl-5(R)-phenylpyrrolidinone-1-yl)-2(R)-phenylethanol 

Relevant articles and documents

Stereocontrolled synthesis of chiral secondary (α-methylene-β-substituted)-γ-lactams by addition of β-functional crotylzinc reagents to chiral imines

Stereocontrolled addition of functionalised crotylzinc reagents to chiral imines derived either from N-α-aminoesters or N-β-aminoalcohols furnished secondary α-methylene-β-substituted-γ-lactams in excellent diastereoisomeric excess (de ≈ 92-100%). Copyrig