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1H-Indole, 7-chloro-3-(4-piperidinyl)- is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

180160-70-7

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180160-70-7 Usage

Synonyms

AG-1296

Chemical class

Indole derivatives

Main property

Highly potent and selective inhibitor of platelet-derived growth factor (PDGF) receptor tyrosine kinase

+ Molecular weight

262.76 g/mol

+ Appearance

Solid

+ Solubility

Soluble in dimethyl sulfoxide (DMSO), poorly soluble in water

+ Mechanism of action

Inhibition of PDGF receptor tyrosine kinase activity

+ Potential therapeutic applications

Treatment of cancer and fibrotic disorders

+ Research use

Tool for understanding the role of PDGF receptors in cellular signaling pathways

Check Digit Verification of cas no

The CAS Registry Mumber 180160-70-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,0,1,6 and 0 respectively; the second part has 2 digits, 7 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 180160-70:
(8*1)+(7*8)+(6*0)+(5*1)+(4*6)+(3*0)+(2*7)+(1*0)=107
107 % 10 = 7
So 180160-70-7 is a valid CAS Registry Number.

180160-70-7Relevant academic research and scientific papers

COMPOUNDS HAVING EFFECTS ON SEROTONIN-RELATED SYSTEMS

-

, (2008/06/13)

A series of hetero-oxy alkanamines are effective pharmaceuticals for the treatment of conditions related to or affected by the reuptake of serotonin and by the serotonin 1 A receptor. The compounds are particularly useful for alleviating the symptoms of n

Compounds having effects on serotonin-related systems

-

, (2008/06/13)

A series of hetero-oxy alkanamines are effective pharmaceuticals for the treatment of conditions related to or affected by the reuptake of serotonin and by the serotonin 1A receptor. The compounds are particularly useful for alleviating the sym

COMPOUNDS HAVING EFFECTS ON SEROTONIN-RELATED SYSTEMS

-

, (2008/06/13)

A series of hetero-oxy alkanamines are effective pharmaceuticals for the treatment of conditions related to or affected by the reuptake of serotonin and by the serotonin 1 A receptor. The compounds are particularly useful for alleviating the symptoms of n

COMPOUNDS HAVING EFFECTS ON SEROTONIN-RELATED SYSTEMS

-

, (2008/06/13)

A series of hetero-oxy alkanamines are effective pharmaceuticals for the treatment of conditions related to or affected by the reuptake of serotonin and by the serotonin 1 A receptor. The compounds are particularly useful for alleviating the symptoms of n

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