180161-75-5

Usage

Uses

Used in Pharmaceutical Industry:
2-(4-chlorophenyl)-2,3-dihydro-1H-pyrrolo[3,4-b]quinolin-1-one is used as a kinase inhibitor for its potential role in cancer treatment. The presence of the 4-chlorophenyl group allows for specific interactions with target enzymes, which may improve the compound's potency and selectivity in inhibiting the activity of enzymes that contribute to cancer cell growth and proliferation. Ongoing research aims to further understand its pharmacological properties and evaluate its potential therapeutic uses in oncology.

Upstream product

• 106-47-8 4-chloro-aniline 
• 180161-74-4 ethyl 2-(chloromethyl)-3-quinolinecarboxylate 
• 62-53-3 aniline 

Downstream Products

• 180161-78-8 2-(4-Chloro-phenyl)-1-oxo-2,3-dihydro-1H-pyrrolo[3,4-b]quinoline-3-carboxylic acid methyl ester 
• 180161-76-6 (E)-[2-(4-chlorophenyl)-1,2-dihydro-1-oxo-3H-pyrrolo[3,4-b]quinolin-3-ylidene]acetic acid 
• 180161-80-2 [2-(4-Chloro-phenyl)-1-oxo-2,3-dihydro-1H-pyrrolo[3,4-b]quinolin-3-yl]-acetic acid 
• 180161-79-9 2-(4-Chloro-phenyl)-3-ethoxycarbonylmethyl-1-oxo-2,3-dihydro-1H-pyrrolo[3,4-b]quinoline-3-carboxylic acid methyl ester 
• 1026695-48-6 C₂₄H₂₁ClN₂O₅ 
• 1028684-23-2 (E)-2-(4-chlorophenyl)-2,3-dihydro-3-[2-(dimethylamino)ethylidene]-1H-pyrrolo[3,4-b]quinolin-1-one 

Relevant academic research and scientific papers

Synthesis and structure-activity relationship studies in peripheral benzodiazepine receptor ligands related to alpidem

The exploration of the structure-affinity relationships concerning a new class of peripheral benzodiazepine receptor (PBR) ligands related to alpidem has been pursued in order to evaluate the consistency of the structure-affinity relationships among diffe

Molecular basis of peripheral vs central benzodiazepine receptor selectivity in a new class of peripheral benzodiazepine receptor ligands related to alpidem

Alpidem (1), the anxiolytic imidazopyridine, has nanomolar binding affinity for both the central benzodiazepine receptor (cbr) and the peripheral benzodiazepine receptor (pbr). A novel class of pbr ligands related to alpidem has been designed by comparing