18018-02-5Relevant articles and documents
Diastereoselective Palladium-Catalyzed Conjugate Addition of Arylboronic Acids to α-Substituted Cyclic Enones
Gao, Ang,Liu, Xiu-Yan,Ding, Chang-Hua,Hou, Xue-Long
supporting information, p. 2829 - 2832 (2017/10/07)
A palladium-catalyzed conjugate addition of arylboronic acids to α-substituted cyclic enones was developed to give α,β-disubstituted ketones with high diastereoselectivity. Mechanistic investigation showed that the high diastereoselectivity was realized through epimerization.
Ultrasound in Organic Synthesis. 7. Preparation of Organozinc Reagents and Their Nickel-Catalyzed Reactions with α,β-Unsaturated Carbonyl Compounds
Petrier, Christian,Barbosa, Jayne C. de Souza,Dupuy, Claude,Luche, Jean-Louis
, p. 5761 - 5765 (2007/10/02)
Diorganozinc compounds can be prepared with great ease and efficiency in a one-pot process, by sonication of lithium, an organic halide, and a zinc halide in THF or toluene mixtures.The reagents thus obtained give rise to clean and selective conjugate additions to α,β-unsaturated aldehydes and ketones in the presence of catalytic amounts of nickel acetylacetonate.
