Cas 180183-08-8,(2S,2'S,2S,4R)-N-{2-[2'-(tert-butoxycarbonyl)amino-2'-(4-isopropyl-5-oxo-tetrahydrofuran-2-yl)-ethyl]-3-methylbutyl}-2-(3-methoxypropoxy)-benzamide

180183-08-8

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Basic information

Product Name: (2S,2'S,2S,4R)-N-{2-[2'-(tert-butoxycarbonyl)amino-2'-(4-isopropyl-5-oxo-tetrahydrofuran-2-yl)-ethyl]-3-methylbutyl}-2-(3-methoxypropoxy)-benzamide
Synonyms: (2S,2'S,2S,4R)-N-{2-[2'-(tert-butoxycarbonyl)amino-2'-(4-isopropyl-5-oxo-tetrahydrofuran-2-yl)-ethyl]-3-methylbutyl}-2-(3-methoxypropoxy)-benzamide
CAS NO:180183-08-8
Molecular Formula:
Molecular Weight: 548.72
EINECS: N/A
Product Categories: N/A

Chemical Properties

Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Appearance: N/A
Density: N/A
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
CAS DataBase Reference: (2S,2'S,2S,4R)-N-{2-[2'-(tert-butoxycarbonyl)amino-2'-(4-isopropyl-5-oxo-tetrahydrofuran-2-yl)-ethyl]-3-methylbutyl}-2-(3-methoxypropoxy)-benzamide(CAS DataBase Reference)
NIST Chemistry Reference: (2S,2'S,2S,4R)-N-{2-[2'-(tert-butoxycarbonyl)amino-2'-(4-isopropyl-5-oxo-tetrahydrofuran-2-yl)-ethyl]-3-methylbutyl}-2-(3-methoxypropoxy)-benzamide(180183-08-8)
EPA Substance Registry System: (2S,2'S,2S,4R)-N-{2-[2'-(tert-butoxycarbonyl)amino-2'-(4-isopropyl-5-oxo-tetrahydrofuran-2-yl)-ethyl]-3-methylbutyl}-2-(3-methoxypropoxy)-benzamide(180183-08-8)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 180183-08-8(Hazardous Substances Data)

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Check Digit Verification of cas no

The CAS Registry Mumber 180183-08-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,0,1,8 and 3 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 180183-08:
(8*1)+(7*8)+(6*0)+(5*1)+(4*8)+(3*3)+(2*0)+(1*8)=118
118 % 10 = 8
So 180183-08-8 is a valid CAS Registry Number.

180183-08-8Upstream product

180183-06-6 (2S,4S,5S,7R)-N-[4-(tert-butoxycarbonyl)amino-7-butylcarbamoyl-5-hydroxy-2-isopropyl-octyl]-2-(3-methoxypropoxy)-benzamide

180183-08-8Downstream Products

179995-61-0 (2S,4S,5S,7R)-N-{4-(tert-butoxycarbonyl)amino-5-hydroxy-2-isopropyl-7-[(2-morpholin-4-ylethyl)-carbamoyl]-octyl}-2-(3-methoxypropoxy)-benzamide

180183-08-8Relevant academic research and scientific papers

METHODS OF TREATING ALZHEIMER’S DISEASE USING AROMATICALLY SUBSTITUTED ω-AMINO-ALKANOIC ACID AMIDES AND ALKANOIC ACID DIAMIDES

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Page 229, (2010/02/05)

Disclosed.are methods for treating Alzheimer's disease, and other diseases, and/or inhibiting beta-secretase enzyme, and/or inhibiting deposition of A beta peptide in a mammal, by use of compounds of formula (I) wherein the variables R1, R2, R3, R4, R5, X1, and X2 are defined herein.

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