180201-14-3Relevant academic research and scientific papers
Synthesis of chiral bis-oxazines: A preliminary assessment of helical conformational framework
Talele, Harish R.,Bedekar, Ashutosh V.
, p. 8579 - 8582 (2012)
A series of novel naphthalene attached bis-oxazines were synthesized and characterized. The bis-oxazines were studied by VT-NMR analysis to assess the possibility of conformational twist. The bis-oxazine prepared from (l)-methylvalinate show a helical conformational twist in the single crystal X-ray analysis. Three isomers of bis-oxazines were prepared from chiral α-methylbenzyl amines, the meso isomer showed small optical rotation probably indicating the helical conformational twist in the molecule.
