HM-61713 (BI-1482694) is a novel, potent, and selective phosphodiesterase 10A (PDE10A) inhibitor that is being investigated as a potential treatment for various central nervous system disorders, including schizophrenia and Huntington's disease. It modulates neurotransmission in the striatum, a key brain region implicated in the pathophysiology of these disorders, by inhibiting the enzyme PDE10A, which is involved in the regulation of dopamine and cAMP signaling in the brain.
1802181-20-9
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Basic information
- Product Name: HM-61713 (BI-1482694)
- Synonyms: HM-61713 (BI-1482694);HM-61713
- CAS NO:1802181-20-9
- Molecular Formula:
- Molecular Weight: 0
- EINECS: -0
- Product Categories: N/A
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: /
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: N/A
- CAS DataBase Reference: HM-61713 (BI-1482694)(CAS DataBase Reference)
- NIST Chemistry Reference: HM-61713 (BI-1482694)(1802181-20-9)
- EPA Substance Registry System: HM-61713 (BI-1482694)(1802181-20-9)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 1802181-20-9(Hazardous Substances Data)
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1802181-20-9 Usage
Uses
Used in Pharmaceutical Industry:HM-61713 (BI-1482694) is used as a potential treatment for central nervous system disorders such as schizophrenia and Huntington's disease. Its application is based on its ability to modulate neurotransmission in the striatum by inhibiting the PDE10A enzyme, which plays a crucial role in the regulation of dopamine and cAMP signaling in the brain.
Used in Neurotransmission Modulation:
HM-61713 (BI-1482694) is used as a neurotransmission modulator for the treatment of central nervous system disorders. Its application is due to its inhibitory effect on the PDE10A enzyme, which is involved in the regulation of neurotransmission in the striatum, a key brain region implicated in the pathophysiology of disorders like schizophrenia and Huntington's disease.
Used in Preclinical Research:
HM-61713 (BI-1482694) is used as a research compound in preclinical studies to evaluate its pharmacokinetic profile and target engagement in the brain. Its application in preclinical research is based on the robust and sustained target engagement demonstrated by the compound, making it a promising candidate for further clinical development.
Check Digit Verification of cas no
The CAS Registry Mumber 1802181-20-9 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,8,0,2,1,8 and 1 respectively; the second part has 2 digits, 2 and 0 respectively.Calculate Digit Verification of CAS Registry Number 1802181-20:
(9*1)+(8*8)+(7*0)+(6*2)+(5*1)+(4*8)+(3*1)+(2*2)+(1*0)=129
129 % 10 = 9
So 1802181-20-9 is a valid CAS Registry Number.
1802181-20-9Upstream product
1802181-20-9Downstream Products
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HM-61713 (BI-1482694)
