180258-96-2 Usage
Uses
Used in Pharmaceutical Applications:
2-(1-adamantyl)pyrrolidine(SALTDATA: HCl) is used as a pharmaceutical candidate for its potential therapeutic properties. Its unique structure may contribute to the development of new drugs or drug delivery systems, targeting specific medical conditions.
Used in Research Applications:
In the field of research, 2-(1-adamantyl)pyrrolidine(SALTDATA: HCl) serves as a valuable compound for studying the effects of pyrrolidine derivatives and adamantyl groups on various biological and chemical processes. It can be instrumental in advancing scientific understanding and innovation.
Used in Organic Synthesis:
2-(1-adamantyl)pyrrolidine(SALTDATA: HCl) is used as a building block in organic synthesis for creating more complex molecules. Its adamantyl group attachment can influence the reactivity and properties of the synthesized compounds, making it a useful component in the development of novel organic materials.
Used in Chemical Reactions:
As a salt form, 2-(1-adamantyl)pyrrolidine(SALTDATA: HCl) is used in various chemical reactions to facilitate processes that require the presence of a stable and soluble compound. Its improved solubility and stability can enhance the efficiency and effectiveness of these reactions.
Used in Drug Delivery Systems:
2-(1-adamantyl)pyrrolidine(SALTDATA: HCl) may be utilized in the development of drug delivery systems, where its enhanced solubility and stability can improve the bioavailability and therapeutic efficacy of drugs. This can be particularly beneficial in the design of targeted drug delivery platforms.
Check Digit Verification of cas no
The CAS Registry Mumber 180258-96-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,0,2,5 and 8 respectively; the second part has 2 digits, 9 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 180258-96:
(8*1)+(7*8)+(6*0)+(5*2)+(4*5)+(3*8)+(2*9)+(1*6)=142
142 % 10 = 2
So 180258-96-2 is a valid CAS Registry Number.
InChI:InChI=1/C14H23N.ClH/c1-2-13(15-3-1)14-7-10-4-11(8-14)6-12(5-10)9-14;/h10-13,15H,1-9H2;1H
180258-96-2Relevant academic research and scientific papers
Kolocouris, Nicolas,Kolocouris, Antonios,Foscolos, George B.,Fytas, George,Neyts, Johan,Padalko, Elisabeth,Balzarini, Jan,Snoeck, Robert,Andrei, Graciela,De Clercq, Erik
, p. 3307 - 3318 (1996)
The synthesis of some new aminoadamantane derivatives is described. The new compounds were evaluated against a wide range of viruses [influenza A H1N1, influenza A H2N2, influenza A H3N2, influenza B, parainfluenza 3, herpes simplex virus type 1 (HSV-1) and type 2 (HSV-2), thymidine kinase- deficient (TK-) HSV-1, vaccinia, vesicular stomatitis, polio 1, Coxsackie B4, Sindbis, Semliki forest, Reo 1, varicella-zoster virus (VZV), TK- VZV, human cytomegalovirus (HCMV), and human immunodeficiency virus type 1 (HIV- 1) and type 2 (HIV-2)]. Some of them proved markedly active against the influenza A H2N2 (compounds 4a,b, 5a, 6a, and 7a), H3N2 (compounds 5a, 6a, and 7a), and H1N1 (compounds 4b,c and 6d). Since compounds 5a, 6a, and 7a, amantadine, and rimantadine showed the same comparative pattern of potency against influenza strains H2N2, H3N2, and B, it may postulated that they act according to a similar mechanism, with regard to their 'amine' effect, on the M2 ion channel of influenza A (H1N1, H2N2, or H3N2). In general, no significant activity was noted with any of the new compounds against any of the other viruses tested, making their activity against influenza virus more specific and striking. Borderline activity was noted with some of the compounds (4b,c, 5a-c, and 8a) against HIV-1.
