18028-56-3Relevant academic research and scientific papers
New trimethoxybenzamides and trimethoxyphenylureas derived from dimethylcarbazole as cytotoxic agents. Part i
Panno, Antonella,Sinicropi, Maria Stefania,Caruso, Anna,El-Kashef, Hussein,Lancelot, Jean-Charles,Aubert, Geneviève,Lesnard, Aurélien,Cresteil, Thierry,Rault, Sylvain
, p. E294-E302 (2014/11/08)
A convenient synthesis of novel functionalized 1,4-dimethylcarbazole derivatives containing 3,4,5-trimethoxybenzamido-ureido or N-(3,4,5- trimethoxyphenyl)ureido group starting from their corresponding indole derivatives is reported. Three derivatives pre
Microwave-assisted solid-acid-catalyzed friedel-crafts alkylation and electrophilic annulation of indoles using alcohols as alkylating agents
Kulkarni, Aditya,Quang, Phong,Toeroek, Bela
experimental part, p. 4010 - 4014 (2010/04/02)
Alcohols are considered environmentally benign alkylating agents since the only by-product generated in their reactions is water. Herein, we report a microwave-assisted Friedel-Crafts alkylation and electrophilic annulation of indoles using alcohols as al
Solvent-free solid acid-catalyzed electrophilic annelations: A new green approach for the synthesis of substituted five-membered N-heterocycles
Abid, Mohammed,Spaeth, Andrew,Toeroek, Bela
, p. 2191 - 2196 (2007/10/03)
An effective microwave-induced, solid acid-catalyzed, environmentally benign synthesis of substituted pyrroles, indoles and carbazoles under solvent-free conditions is described. The new synthetic methodology is based on the use of a considerably strong solid acid, K-10 montmorillonite. Both the cyclialkylation of amines and annelation of pyrroles and indoles have been completed within minutes and provided excellent (75-98%) yields with practically 100% selectivity.
