180295-25-4Relevant academic research and scientific papers
A novel and efficient method for the synthesis of tetrahydropyranyl ethers catalyzed by Sc(OTf)3
Watahiki, Tsutomu,Kikumoto, Hisashi,Matsuzaki, Masaya,Suzuki, Takeshi,Oriyama, Takeshi
, p. 367 - 368 (2007/10/03)
Reaction of alcohols with dihydropyran in the presence of a catalytic amount of Sc(OTf)3 provides efficiently the corresponding tetrahydropyranyl ethers. After the reaction, the catalyst can be recovered quantitatively from the aqueous media and reused without loss of the activity.
A novel and chemoselective transformation of alcohol silyl ethers into the corresponding tetrahydropyranyl ethers
Suzuki,Oriyama
, p. 555 - 558 (2007/10/03)
Direct conversion of alcohol silyl ethers into the corresponding tetrahydropyranyl (THP) ethers can be easily performed by reaction with THP acetate under the influence of a catalytic amount of tert-butyldimethylsilyl trifluoromethanesulfonate (TB-SOTf). Aliphatic TBS ether can be selectively transformed into the corresponding THP ether in the presence of phenolic TBS ether.
