180312-50-9Relevant academic research and scientific papers
Novel, potent and selective chimeric FXa inhibitors featuring hydrophobic P1-ketoamide moieties
Semple,Levy, Odile E.,Minami, Nathaniel K.,Owens, Timothy D.,Siev, Daniel V.
, p. 2305 - 2309 (2007/10/03)
Judicious combination of P-region sequences of highly potent anticoagulant proteins including NAP5, NAP6, Ecotin, and Antistasin with SAR from small molecule FXa inhibitors led to a series of chimeric inhibitors of formula 1a-j. We report herein the desig
