18032-57-0Relevant articles and documents
A novel reagent combination for the oxidation of highly electron deficient pyridines to N-oxides: trifluoromethanesulfonic anhydride/sodium percarbonate
Zhu, Xizhen,Kreutter, Kevin D.,Hu, Huaping,Player, Mark R.,Gaul, Micheal D.
, p. 832 - 834 (2008/04/13)
A novel reagent combination, Tf2O/Na2CO3·1.5H2O2, has been developed for the oxidation of highly electron deficient pyridines to their corresponding N-oxides. The N-oxidation reaction, utilizing the in situ generated peracid, proceeds under mild conditions that allow for a number of functional groups and substitution patterns on the pyridine ring.