180335-90-4

Basic information

• Product Name: Phosphoric acid (2R,3S,5R)-3-[bis-(4-methoxy-phenyl)-phenyl-methoxy]-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-2-ylmethyl ester hexadecyl ester (2R,3S,4S,5R,6S)-3,4,5-trihydroxy-6-methoxy-tetrahydro-pyran-2-ylmethyl ester
• Synonyms: Phosphoric acid (2R,3S,5R)-3-[bis-(4-methoxy-phenyl)-phenyl-methoxy]-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-2-ylmethyl ester hexadecyl ester (2R,3S,4S,5R,6S)-3,4,5-trihydroxy-6-methoxy-tetrahydro-pyran-2-ylmethyl ester
• CAS NO: 180335-90-4
• Molecular Weight: 1025.18
• Mol File: 180335-90-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Phosphoric acid (2R,3S,5R)-3-[bis-(4-methoxy-phenyl)-phenyl-methoxy]-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-2-ylmethyl ester hexadecyl ester (2R,3S,4S,5R,6S)-3,4,5-trihydroxy-6-methoxy-tetrahydro-pyran-2-ylmethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Phosphoric acid (2R,3S,5R)-3-[bis-(4-methoxy-phenyl)-phenyl-methoxy]-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-2-ylmethyl ester hexadecyl ester (2R,3S,4S,5R,6S)-3,4,5-trihydroxy-6-methoxy-tetrahydro-pyran-2-ylmethyl ester(180335-90-4)
• EPA Substance Registry System: Phosphoric acid (2R,3S,5R)-3-[bis-(4-methoxy-phenyl)-phenyl-methoxy]-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-2-ylmethyl ester hexadecyl ester (2R,3S,4S,5R,6S)-3,4,5-trihydroxy-6-methoxy-tetrahydro-pyran-2-ylmethyl ester(180335-90-4)

Safety Data

• Hazardous Substances Data: 180335-90-4(Hazardous Substances Data)

Upstream product

• 50-89-5 thymidine 
• 180335-81-3 3'-O-(4,4'-dimethoxytrityl)-5'-O-(4-nitrobenzoyl)thymidine 
• 5983-14-2 5'-O-(4-nitrobenzoyl)thymidine 
• 98288-62-1 hexadecyl phosphorodichloridite 
• 76054-81-4 3'-O-(4,4'-dimethoxytrityl)thymidine 
• 36653-82-4 1-Hexadecanol 
• 97-30-3 methyl-alpha-D-glucopyranoside 

Relevant articles and documents

Straightforward synthesis of lipophilic thymidine glucopyranosyl monophosphates as models for a drug delivery system across cellular membranes

O-methyl (3'-6) and (5'-6) thymidinyl gluco- and mannopyranosides and (3'-6) thymidinyl glucofuranose can be synthesised in excellent yields by applying the phosphotriester method. The lipophilic phosphotriesters thus obtained are designed as carriers of nucleoside drugs across cellular membranes.