180339-54-2

Basic information

• Product Name: 6-(2,4-difluoro-benzoylamino)-nicotinic acid
• CAS NO: 180339-54-2
• Molecular Weight: 278.215
• Mol File: 180339-54-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 6-(2,4-difluoro-benzoylamino)-nicotinic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 6-(2,4-difluoro-benzoylamino)-nicotinic acid(180339-54-2)
• EPA Substance Registry System: 6-(2,4-difluoro-benzoylamino)-nicotinic acid(180339-54-2)

Safety Data

• Hazardous Substances Data: 180339-54-2(Hazardous Substances Data)

Upstream product

• 72482-64-5 2,4-difluorobenzoyl chloride 
• 39658-41-8 ethyl-6-amino-nicotinate 
• 201686-67-1 6-[bis-(2,4-difluoro-benzoyl)-amino]-nicotinic acid ethyl ester 

Relevant articles and documents

5-Fluoro-2-methyl-N-[5-(5H-pyrrolo[2,1-c][1,4]benzodiazepine-10(11H)-yl carbonyl)-2-pyridinyl]benzamide (CL-385004) and analogs as orally active arginine vasopressin receptor antagonists

Synthesis and structure-activity relationships (SAR) of orally active arginine vasopressin (AVP) receptor antagonists are discussed. Potent and orally active AVP receptor antagonists are produced when ring A of VPA-985 (1) is replaced with a 3-pyridinyl unit (2b).