18034-03-2

Basic information

• Product Name: 2,3-dimethoxy[1,3]benzodioxolo[5,6-c]phenanthridine
• CAS NO: 18034-03-2
• Molecular Formula: C₂₀H₁₅NO₄
• Molecular Weight: 333.3374
• Mol File: 18034-03-2.mol
• Article Data: 19

Chemical Properties

• Boiling Point: 554.3°C at 760 mmHg
• Flash Point: 194.2°C
• Density: 1.365g/cm³
• Vapor Pressure: 9.27E-12mmHg at 25°C
• Refractive Index: 1.729
• CAS DataBase Reference: 2,3-dimethoxy[1,3]benzodioxolo[5,6-c]phenanthridine(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3-dimethoxy[1,3]benzodioxolo[5,6-c]phenanthridine(18034-03-2)
• EPA Substance Registry System: 2,3-dimethoxy[1,3]benzodioxolo[5,6-c]phenanthridine(18034-03-2)

Safety Data

• Hazardous Substances Data: 18034-03-2(Hazardous Substances Data)

Usage

Chemical class

benzodioxole and phenanthridine derivatives

Molecular structure

complex and unique

Functional groups

two methoxy groups

Type of compound

phenolic ether

Potential applications

medicinal chemistry and drug discovery

Need for further research

to understand biological activities and therapeutic uses

Upstream product

• 54022-61-6 11,12-dihydro-8,9-dimethoxy-2,3-methylenedioxybenzo[c]phenanthridine 
• 250253-62-4 C₂₀H₁₈BrNO₄ 
• 5392-10-9 2-bromo-4,5-dimethoxybenzaldehyde 
• 18093-05-5 6-chloroverataldehyde 
• 13063-06-4 dihydronitidine 
• 98799-33-8 2-iodo-4,5-dimethoxybenzylamine 
• 62848-88-8 trans-4-<3,4-(methylenedioxy)phenyl>but-3-enoic acid 
• 120-57-0 piperonal 
• 180411-13-6 2-(6-bromo-naphtho[2,3-d][1,3]dioxol-5-yloxy)-2-methylpropionamide 
• 213698-51-2 N-(6-bromonaphtho[2,3-d][1,3]dioxol-5-yl)-2-hydroxy-2-methylpropionamide 
• 180411-19-2 N-(6-Bromo-naphtho[2,3-d][1,3]dioxol-5-yl)-formamide 
• 180411-09-0 6,6-dibromo-7,8-dihydro-6H-naphtho[2,3-d][1,3]dioxol-5-one 
• 180411-11-4 6-bromonaphtho[2,3-d][1,3]dioxol-5-ol 
• 180411-17-0 2-bromo-6,7-methylenedioxy-1-naphthylamine 

Downstream Products

• 13063-06-4 dihydronitidine 
• 13063-04-2 nitidine chloride 
• 41349-33-1 5,6-dihydro-6-methoxynitidine 
• 548-31-2 oxynitidine 
• 41349-35-3 Nitidine methyl sulfate 
• 119276-08-3 2,3-dimethoxy-12-methyl-[1,3]dioxolo[4',5':4,5]benzo[1,2-c]phenanthridinium; acetate 

Relevant articles and documents

TOTAL SYNTHESIS OF N-NORNITIDINE

The benzophenanthridine alkaloid, N-nornitidine has been synthesized employing a benzyne-vinyl isocyanate cycloaddition as the key transformation.

Studies in synthetic photochemistry I synthesis of naphthaphenanthridine alkaloids

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A concise synthesis of nornitidine via nickel- or palladium-catalyzed annulation

A concise method to synthesize benzo[c]phenanthridine alkaloid, nornitidine, was developed utilizing nickel- or palladium-catalyzed iminoannulation of an internal alkyne. The advantages of this strategy included readily available starting materials, inexp

Visible-light-promoted iminyl-radical formation from Acyl oximes: A unified approach to pyridines, quinolines, and phenanthridines

A unified strategy involving visible-light-induced iminyl-radical formation has been established for the construction of pyridines, quinolines, and phenanthridines from acyl oximes. With fac-[Ir(ppy)3] as a photoredox catalyst, the acyl oximes were converted by 1 e- reduction into iminyl radical intermediates, which then underwent intramolecular homolytic aromatic substitution (HAS) to give the N-containing arenes. These reactions proceeded with a broad range of substrates at room temperature in high yield. This strategy of visible-light-induced iminyl-radical formation was successfully applied to a five-step concise synthesis of benzo[c]phenanthridine alkaloids.