180348-14-5Relevant academic research and scientific papers
A lithiomethyl trimethylammonium reagent as a methylene donor
Den Hartog, Tim,Sarria Toro, Juan M.,Couzijn, Erik P. A.,Chen, Peter
, p. 10604 - 10607 (2014)
Straightforward deprotonation of soluble tetramethylammonium salts with alkyllithium reagents gives lithiomethyl trimethylammonium reagents. Coordination of the Li cation is crucial to the stability of these 'N-C ylides'. These reagents were used to prepare epoxides, aziridines and allylic alcohols. This journal is the Partner Organisations 2014.
New synthetic routes to 2-fluoro-2-phenylalkanoic acids
Goj, Olav,Haufe, Guenter
, p. 1289 - 1294 (2007/10/03)
2-Fluoro-2-phenylalkanoic acids 2 are obtained by oxidation of the corresponding β-fluoro-β-phenyl alcohols 6. These compounds are shown to be accessible by two alternative pathways, either by bromo fluorination of α-alkyl styrenes 3, subsequent bromine-b
