180479-44-1Relevant articles and documents
Diastereoselective addition of organolithiums to new chiral hydrazones. Enantioselective synthesis of (R)-coniine
Kim, Yong Hae,Choi, Jun Young
, p. 5543 - 5546 (2007/10/03)
The reactions of organolithiums with the new chiral hydrazones derived from (S)-indoline-2-carboxylic acid afforded chiral hydrazines with high diastereoselectivities (up to 99% de) and the present method was utilized for the preparation of high optically pure (R)-coniine (94% ee).