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Metaphanine is an alkaloid that was first isolated from the stems of Stephania japonica Miers and later discovered in S. abyssinica. It was initially thought to be optically inactive, but recent determinations show it has an optical rotation of [α]25D ~ 21° (c 1.0, CHC13). The original molecular formula of C15H29O3N has been revised to the current one. Metaphanine exhibits two absorption maxima at 205 and 285 nm in the ultraviolet spectrum in ethanol. The alkaloid can be converted into a monoacetate with a melting point of 150°C, and its structure has been primarily determined from the mass spectrum.

1805-86-3

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1805-86-3 Usage

Uses

1. Used in Pharmaceutical Industry:
Metaphanine is used as a pharmaceutical compound for its potential therapeutic applications. The expression is: "Metaphanine is used as a pharmaceutical compound for its potential therapeutic applications."
2. Used in Research and Development:
Metaphanine is used as a research compound for studying its chemical properties, structure, and potential interactions with other molecules. The expression is: "Metaphanine is used as a research compound for studying its chemical properties, structure, and potential interactions with other molecules."
3. Used in Drug Development:
Metaphanine may be used as a starting material or a lead compound in the development of new drugs, particularly those targeting specific receptors or biological pathways. The expression is: "Metaphanine is used as a starting material or a lead compound in drug development."
4. Used in Toxicology Studies:
Metaphanine can be utilized in toxicology studies to understand its effects on biological systems and to evaluate its safety profile. The expression is: "Metaphanine is used in toxicology studies to understand its effects on biological systems and to evaluate its safety profile."
5. Used in Natural Product Chemistry:
Metaphanine serves as an example of a naturally occurring alkaloid, contributing to the understanding of the chemical diversity found in nature. The expression is: "Metaphanine is used in natural product chemistry to contribute to the understanding of the chemical diversity found in nature."

References

Kondo, Sanada., J. Pharrn. Soc., Japan, 44, 5 (1924) Kondo, Sanada., ibid, 47, 31, 126 (1927) Kondo, Sanada., ibid, 48,163 (1928) Tomita et ai., Tetrahedron Lett., 3605 (1964) de Waal, Prinsloo, Arndt., ibid, 6169 (1966) Mass spectrum: Tomita, Kato, Ibuka., Tetrahedron Lett., 1019 (1965)

Check Digit Verification of cas no

The CAS Registry Mumber 1805-86-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,8,0 and 5 respectively; the second part has 2 digits, 8 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1805-86:
(6*1)+(5*8)+(4*0)+(3*5)+(2*8)+(1*6)=83
83 % 10 = 3
So 1805-86-3 is a valid CAS Registry Number.
InChI:InChI=1/C19H23NO5/c1-20-9-8-17-7-6-14(21)19(22)18(17,20)10-13(25-19)11-4-5-12(23-2)16(24-3)15(11)17/h4-5,13,22H,6-10H2,1-3H3/t13-,17+,18-,19-/m0/s1

1805-86-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name 8β,10β-epoxy-8α-hydroxy-3,4-dimethoxy-17-methyl-hasubanan-7-one

1.2 Other means of identification

Product number -
Other names 8β,10β-Epoxy-8α-hydroxy-3,4-dimethoxy-17-methyl-hasubanan-7-on

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1805-86-3 SDS

1805-86-3Downstream Products

1805-86-3Relevant academic research and scientific papers

Enantioselective total synthesis of (+)-stephadiamine through bioinspired aza-benzilic acid type rearrangement

Odagi, Minami,Matoba, Taisei,Hosoya, Keisuke,Nagasawa, Kazuo

, p. 2699 - 2704 (2021/03/01)

We report the first enantioselective total syntheses of the hasubanan alkaloid (-)-metaphanine and the norhasubanan alkaloid (+)-stephadiamine. Key features of these syntheses include diastereoselective oxidative phenolic coupling reaction and subsequent

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