180506-33-6Relevant academic research and scientific papers
Efficient synthesis of a key intermediate of DV-7751 via optical resolution or microbial reduction
Miyadera, Akihiko,Satoh, Koji,Imura, Akihiro
, p. 563 - 565 (2007/10/03)
Two efficient and practical methods of synthesis of the C-10 substituent of DV-7751 (1), a novel quinolone carboxylic acid, were established. The first method utilizes an optical resolution of racemic 8-amino-6-benzyl-6- azaspiro[3.4]octane (13), while th
