18059-99-9 Usage
Uses
Used in Pharmaceutical Industry:
5H-dibenzo[a,d]cyclohepten-5-one O-[2-(methylamino)ethyl]oxime monohydrochloride is used as a tricyclic antidepressant for the treatment of major depressive disorder. Its chemical structure allows it to interact with specific receptors in the brain, modulating the levels of neurotransmitters and providing relief from depressive symptoms.
Used in Antibacterial Applications:
In the field of antibacterial research, 5H-dibenzo[a,d]cyclohepten-5-one O-[2-(methylamino)ethyl]oxime monohydrochloride serves as a potential new agent. Its unique chemical properties may enable it to target bacterial cells in novel ways, offering an alternative to existing antibiotics and potentially overcoming issues of antibiotic resistance.
Used in Drug Delivery Systems:
Similar to gallotannin, 5H-dibenzo[a,d]cyclohepten-5-one O-[2-(methylamino)ethyl]oxime monohydrochloride may also benefit from advancements in drug delivery systems. By employing carriers such as organic and metallic nanoparticles, the compound's delivery, bioavailability, and therapeutic outcomes could be improved, enhancing its effectiveness in various applications.
Originator
Deparon,Aron,France,1981
Manufacturing Process
1.15 g of Na are dissolved in 100 ml of absolute ethanol; 10 g of 5-oximino5H-dibenzo[a,d]cycloheptene are introduced, followed by boiling under reflux
for 1 hour and evaporation to dryness. The residue is dissolved in
dimethylformamide and part of the solvent is distilled off. The solution is now
cooled to about 20°C and there are added 5.3 g of methylaminoethyl chloride
which is prepared below 10°C from the corresponding hydrochloride by
supersaturation with potassium carbonate. The mixture is then heated to
100°C for 1? hours. Finally, the mixture is evaporated to dryness, the residue
dissolved in ether/water and the ethereal phase washed with water. After
drying of the ethereal phase with potassium carbonate, 8.5 g of the
hydrochloride of 5-β-methylaminoethoxyimino-5H-dibenzo[a,d]cycloheptene
(melting point 232°C to 233°C) are obtained.
Therapeutic Function
Antidepressant
Check Digit Verification of cas no
The CAS Registry Mumber 18059-99-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,8,0,5 and 9 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 18059-99:
(7*1)+(6*8)+(5*0)+(4*5)+(3*9)+(2*9)+(1*9)=129
129 % 10 = 9
So 18059-99-9 is a valid CAS Registry Number.
InChI:InChI=1/C18H18N2O.ClH/c1-19-12-13-21-20-18-16-8-4-2-6-14(16)10-11-15-7-3-5-9-17(15)18;/h2-11,19H,12-13H2,1H3;1H
