18060-58-7

Upstream product

• 43020-38-8 2,3,4-trimethoxybenzonitrile 
• 925-90-6 ethylmagnesium bromide 

Downstream Products

• 127034-39-3 (E)-2-Methyl-3-phenyl-1-(2,3,4-trimethoxy-phenyl)-propenone 
• 127034-37-1 2-fluoro-2',3',4'-trimethoxychalcone 
• 127034-28-0 1-(2,3,4-trimethoxyphenyl)-3-[4-(diethylamino)phenyl]-2-methylprop-2-en-1-one 
• 127034-40-6 1-(2,3,4-trimethoxyphenyl)-3-[4-(dimethylamino)phenyl]-2-methylprop-2-en-1-one 

Relevant academic research and scientific papers

Propenone derivatives

The present invention relates to propenone derivatives represented by the following formula (I): STR1 wherein R1 represents hydrogen, substituted or unsubstituted lower alkyl, substituted or unsubstituted aryl, or YR5 (wherein Y represents S or O; and R5 represents substituted or unsubstituted lower alkyl, substituted or unsubstituted aryl, substituted or unsubstituted heteroaryl, or a substituted or unsubstituted cyclic ether residue); R2 and R3 independently represent hydrogen, lower alkyl, or substituted or unsubstituted aralkyl, or alternatively R2 and R3 are combined to form substituted or unsubstituted methylene or ethylene; R4 represents hydrogen, hydroxy, lower alkyl, substituted or unsubstituted aralkyl, lower alkoxy, substituted or unsubstituted aralkyloxy, or halogen; and X represents substituted or unsubstituted indolyl; or pharmaceutically acceptable salts thereof.

PROPENONE DERIVATIVES

The present invention relates to propenone derivatives represented by the following formula (I): wherein R1represents hydrogen or lower alkyl; R2and R3independently represent hydrogen, lower alkyl, or substituted or unsubstituted aralkyl, or alternatively R2and R3are combined to form substituted or unsubstituted methylene or ethylene; R4represents hydrogen, hydroxy, lower alkyl, substituted or unsubstituted aralkyl, lower alkoxy, substituted or unsubstituted aralkyloxy, or halogen; and X represents substituted or unsubstituted indolyl, with the proviso that when OR3is on the position 2 or position 6 of the benzene ring, R3is not hydrogen; that when R4is on the position 2 or position 6 of the benzene ring, R4is not hydroxy; and that the combination of OR2, OR3, and R4is not 3,4-dimethoxy or 3,4,5-trimethoxy; or pharmaceutically acceptable salts thereof.