18060-72-5

Basic information

• Product Name: 3-methylsulfanyl-2H-1,2,4-triazin-5-one
• Synonyms: 3-methylsulfanyl-2H-1,2,4-triazin-5-one;1,2,4-Triazin-5(2H)-one,3-(methylthio)-(9CI);3-(Methylsulphanyl)-1,2,4-triazin-5(2H)-one, 2,5-Dihydro-3-(methylthio)-5-oxo-1,2,4-triazine;3-(Methylthio)-1,2,4-triazin-5(2H)-one
• CAS NO: 18060-72-5
• Molecular Formula: C₄H₅N₃OS
• Molecular Weight: 143.17
• Product Categories: THIOL
• Mol File: 18060-72-5.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 233.4°Cat760mmHg
• Flash Point: 94.9°C
• Appearance: /
• Density: 1.53g/cm³
• Vapor Pressure: 0.0561mmHg at 25°C
• Refractive Index: 1.7
• CAS DataBase Reference: 3-methylsulfanyl-2H-1,2,4-triazin-5-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-methylsulfanyl-2H-1,2,4-triazin-5-one(18060-72-5)
• EPA Substance Registry System: 3-methylsulfanyl-2H-1,2,4-triazin-5-one(18060-72-5)

Safety Data

• Hazardous Substances Data: 18060-72-5(Hazardous Substances Data)

Usage

General Description

3-methylsulfanyl-2H-1,2,4-triazin-5-one, also known as prometryn, is a chemical compound commonly used as a herbicide to control broadleaf and grassy weeds in various crops such as cotton, corn, and soybeans. It belongs to the class of triazine herbicides and works by inhibiting photosynthesis in the target plants. Prometryn is a white crystalline solid that is moderately soluble in water and has a molecular formula of C10H19N5OS. It is considered to have low toxicity to mammals but can be harmful to aquatic organisms and bees if not used properly. Due to its potential environmental impact, the use and application of prometryn are regulated in many countries.

InChI:InChI=1/C4H5N3OS/c1-9-4-6-3(8)2-5-7-4/h2H,1H3,(H,6,7,8)

Upstream product

• 626-08-4 6-aza-2-thiouracil 
• 74-88-4 methyl iodide 

Downstream Products

• 6943-94-8 1-methyl-6-azauracil 
• 1384852-57-6 3-(methylthio)-6-(2-oxo-2-phenylethyl)-1,6-dihydro-1,2,4-triazin-5(4H)-one 

Relevant articles and documents

2-HYDROXYIMINOPYRIMIDINE NUCLEOSIDES AND DERIVITIVES AND ANTIVIRAL USES THERETO

Disclosed herein are nucleosides and nucleotides analogs, methods for preparing the same, and methods for treating and/or ameliorating infection caused by a Coronaviridae virus, a Caliciviridae virus, an Orthomyxoviridae virus, a Herpesviridae virus, a Flaviviridae virus, a Filoviridae virus,and a Pneumoviridae virus with one or more nucleoside and nucleotide analogs of formula I. In certain embodiments, compounds and compositions of nucleoside or nucleotide derivatives are disclosed, which can be administered either alone or in combination with other anti-viral agents. In certain embodiments, the compounds are according to Formula (I): or a pharmaceutically acceptable salt, solvate, stereoisomeric form, a tautomeric form or polymorphic form thereof, wherein R1, R2, R3, R4, X, and sugar are as described herein.

3,5-dioxo-(2H,4H)-1,2,4-triazine derivatives as 5HT1A ligands

A 3,5-dioxo-(2H,4H)-1,2,4-triazine compounds of formula I STR1 in which: R1 and R2, which are identical or different, represent hydrogen or C1 -C6 alkyl, n is 2 to 6, inclusive, A represents aryl piperazino II STR2 the Ar grouping representing phenyl, naphthyl, pyrimidyl, or pyridyl, unsubstituted or substituted by C1 -C3 alkyl, C1 -C3 alkoxy, hydroxy, trifluoromethyl, or halogen, or III benzodioxanyl-methyl-amino or pyridodioxanyl-methyl-amino STR3 in which R represents hydrogen or C1 -C3 alkyl and X represents a nitrogen or carbon atom, therapeutically-acceptable salts and enantiomers thereof, pharmaceutical compositions thereof, and method for treatment of diseases requiring a 5HT1A receptor agonist therewith.