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CAS

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180624-04-8

N-tosyl-5-amino-4-iodo-7-methoxyindole is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 180624-04-8 Structure

  • Basic information

    1. Product Name: N-tosyl-5-amino-4-iodo-7-methoxyindole
    2. Synonyms: N-tosyl-5-amino-4-iodo-7-methoxyindole
    3. CAS NO:180624-04-8
    4. Molecular Formula:
    5. Molecular Weight: 442.277
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 180624-04-8.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: N-tosyl-5-amino-4-iodo-7-methoxyindole(CAS DataBase Reference)
    10. NIST Chemistry Reference: N-tosyl-5-amino-4-iodo-7-methoxyindole(180624-04-8)
    11. EPA Substance Registry System: N-tosyl-5-amino-4-iodo-7-methoxyindole(180624-04-8)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 180624-04-8(Hazardous Substances Data)

180624-04-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 180624-04-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,0,6,2 and 4 respectively; the second part has 2 digits, 0 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 180624-04:
(8*1)+(7*8)+(6*0)+(5*6)+(4*2)+(3*4)+(2*0)+(1*4)=118
118 % 10 = 8
So 180624-04-8 is a valid CAS Registry Number.

180624-04-8Relevant articles and documents

Efficient reagents for the synthesis of 5-, 7-, and 5,7-substituted indoles starting from aromatic amines: Scope and limitations

Ezquerra, Jesus,Pedregal, Concepcion,Lamas, Carlos,Barluenga, Jose,Perez, Marta,Garcia-Martin, Miguel Angel,Gonzalez, Jose M.

, p. 5804 - 5812 (2007/10/03)

Upon reaction with IPy2BF4, 4-substituted anilines give regioselectively the corresponding o-iodoanilines in nearly quantitative yield, in a process that can be carried out on a multigram scale. Palladium-catalyzed coupling of the resulting 2-iodoanilines with (trimethylsilyl)acetylene (TMSA), followed by efficient CuI-mediated nitrogen cyclization onto alkynes with concurrent elimination of the TMS substituent, allows a straightforward elaboration of 5-mono- and 5,7-disubstituted indoles from aromatic amines. This new approach to the aforementioned indoles does not requires protective groups on nitrogen at any step and can be adapted for preparing related 7-monosubstituted indoles. Moreover, examples iterating the process are given, allowing bis-annulation and sequential double annulation and resulting in synthesis of benzodipyrroles. Additionally, suitable conditions for iodination of some of the target indoles with IPy2BF4 are discussed.

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