180718-55-2Relevant academic research and scientific papers
Synthesis of α-hydroxy-β-amino acids from chiral cyanohydrins
Warmerdam, Erwin G.J.C.,Van Rijn, Rachel D.,Brussee, Johannes,Kruse, Chris G.,Van Der Gen, Arne
, p. 1723 - 1732 (2007/10/03)
(-)-(R,E)-2-hydroxy-3-pentenenitrile 1, obtained by R-oxynitrilase catalyzed addition of HCN to 2-butenal, was shown to be an excellent chiral starting material for the synthesis of α-hydroxy-β-amino acids of high enantiomeric and diastereomeric purity. T
