180747-36-8

Basic information

• Product Name: Acetamide, 2-bromo-N,N-bis[(4-methoxyphenyl)methyl]-
• CAS NO: 180747-36-8
• Molecular Formula: C18H20BrNO3
• Molecular Weight: 378.266
• Mol File: 180747-36-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Acetamide, 2-bromo-N,N-bis[(4-methoxyphenyl)methyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Acetamide, 2-bromo-N,N-bis[(4-methoxyphenyl)methyl]-(180747-36-8)
• EPA Substance Registry System: Acetamide, 2-bromo-N,N-bis[(4-methoxyphenyl)methyl]-(180747-36-8)

Safety Data

• Hazardous Substances Data: 180747-36-8(Hazardous Substances Data)

Upstream product

• 17061-62-0 N,N-bis(p-methoxybenzyl)amine 
• 598-21-0 2-Bromoacetyl bromide 

Downstream Products

• 880175-70-2 (2R,3S)-N,N-bis(4-methoxybenzyl)-3-phenyl-2-oxiranecarboxamide 

Relevant articles and documents

Highly stereoselective intramolecular Buchner reaction of diazoacetamides catalyzed by a Ru(ii)-Pheox complex

This work reports the first efficient enantioselective intramolecular Buchner reaction of diazoacetamides. The Ru(ii)-Pheox catalyst was shown to be highly efficient in this transformation in terms of both the regio-and enantioselectivity (up to 99% ee) giving the desired products in quantitative yield.

Samarium(II) iodide mediated intermolecular coupling reactions of N,N-dibenzyl-α-haloamides with carbonyl compounds

Samarium(II) iodide mediated coupling reactions of α-haloamides with carbonyl compounds are found to give N,N-dibenzyl-β-hydroxyamides (4a-i, 5a-i, and 6a) in good yields under mild reaction conditions. The transformation of 4a and 5a to N,N-dibenzyl-3-phenylpropanamide (7) and β-hydroxycarboxylic acid (8), respectively, are described.