Dde Biotin-PEG4-DBCO is a cleavable biotin reagent that is reactive with azide moiety via copper-free Click Chemistry. It features a Dde protecting group that allows for efficient release of captured biotinylated molecules from streptavidin under mild conditions with hydrazine.
1807512-43-1
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Basic information
- Product Name: Dde Biotin-PEG4-DBCO
- Synonyms: Dde Biotin-PEG4-DBCO
- CAS NO:1807512-43-1
- Molecular Formula: C47H61N5O9S
- Molecular Weight: 872.08
- EINECS: N/A
- Product Categories: N/A
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Chemical Properties
- Melting Point: N/A
- Boiling Point: 1103.9±65.0 °C(Predicted)
- Flash Point: N/A
- Appearance: /
- Density: 1.29±0.1 g/cm3(Predicted)
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: N/A
- PKA: 13.90±0.40(Predicted)
- CAS DataBase Reference: Dde Biotin-PEG4-DBCO(CAS DataBase Reference)
- NIST Chemistry Reference: Dde Biotin-PEG4-DBCO(1807512-43-1)
- EPA Substance Registry System: Dde Biotin-PEG4-DBCO(1807512-43-1)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 1807512-43-1(Hazardous Substances Data)
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1807512-43-1 Usage
Uses
Used in Biochemical Research:Dde Biotin-PEG4-DBCO is used as a reagent for bioorthogonal labeling and detection of biomolecules in various biochemical research applications. Its copper-free Click Chemistry compatibility enables selective and efficient bioconjugation without the need for copper catalysts, which can be toxic or interfere with biological systems.
Used in Drug Delivery Systems:
In the pharmaceutical industry, Dde Biotin-PEG4-DBCO is used as a component in targeted drug delivery systems. The reagent can be employed to attach drugs or imaging agents to biomolecules, allowing for specific targeting and release of the payload in response to biological triggers or conditions.
Used in Diagnostic Applications:
Dde Biotin-PEG4-DBCO is used as a detection agent in diagnostic assays, taking advantage of its biotin-streptavidin interaction for signal amplification. This property makes it suitable for various diagnostic platforms, including immunoassays and molecular diagnostics, where high sensitivity and specificity are required.
Used in Material Science:
In the field of material science, Dde Biotin-PEG4-DBCO is used as a building block for the development of biocompatible and stimuli-responsive materials. Its ability to form reversible bioconjugates can be exploited to create materials with tunable properties, such as self-healing or drug release capabilities.
Used in Proteomics:
In proteomics research, Dde Biotin-PEG4-DBCO is used as a labeling agent for the enrichment and identification of specific protein populations. The reagent can be employed to selectively label proteins of interest, facilitating their detection and quantification in complex biological samples.
Check Digit Verification of cas no
The CAS Registry Mumber 1807512-43-1 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,8,0,7,5,1 and 2 respectively; the second part has 2 digits, 4 and 3 respectively.Calculate Digit Verification of CAS Registry Number 1807512-43:
(9*1)+(8*8)+(7*0)+(6*7)+(5*5)+(4*1)+(3*2)+(2*4)+(1*3)=161
161 % 10 = 1
So 1807512-43-1 is a valid CAS Registry Number.
1807512-43-1Upstream product
1807512-43-1Downstream Products
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Dde Biotin-PEG4-DBCO
