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Mal-PEG2-PFP is a PEG linker containing maleimide and PFP moieties, designed to enhance the water solubility of compounds in aqueous media. The maleimide group is thiol-reactive and can form thiolester bonds within a specific pH range, while the PFP moiety is amine-reactive and more stable against hydrolysis.

1807512-47-5

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1807512-47-5 Usage

Uses

Used in Pharmaceutical Industry:
Mal-PEG2-PFP is used as a conjugation agent for the development of targeted drug delivery systems. Its thiol-reactive maleimide group allows for selective binding to specific biomolecules, such as antibodies or proteins, enabling the creation of site-specific drug conjugates. This targeted approach can improve the efficacy and reduce the side effects of therapeutic agents.
Used in Bioconjugation:
Mal-PEG2-PFP is used as a bioconjugation agent to link various biological molecules, such as proteins, peptides, or nucleic acids, with other molecules like drugs, fluorophores, or enzymes. The stable PFP amine-reactive group ensures the formation of covalent bonds, facilitating the development of novel bioconjugates with enhanced properties and applications.
Used in Diagnostics:
Mal-PEG2-PFP is used as a component in the development of diagnostic tools, such as imaging agents or biosensors. The hydrophilic PEG linker can improve the solubility and stability of diagnostic molecules, while the reactive maleimide and PFP groups allow for the attachment of signaling or detection moieties, enhancing the sensitivity and specificity of diagnostic assays.
Used in Material Science:
Mal-PEG2-PFP can be used as a building block in the synthesis of biocompatible and hydrophilic materials, such as hydrogels or nanoparticles. The PEG linker provides water solubility and biocompatibility, while the reactive maleimide and PFP groups enable the incorporation of various functional groups or biomolecules, tailoring the properties of the resulting materials for specific applications.

Check Digit Verification of cas no

The CAS Registry Mumber 1807512-47-5 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,8,0,7,5,1 and 2 respectively; the second part has 2 digits, 4 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1807512-47:
(9*1)+(8*8)+(7*0)+(6*7)+(5*5)+(4*1)+(3*2)+(2*4)+(1*7)=165
165 % 10 = 5
So 1807512-47-5 is a valid CAS Registry Number.

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