Bromo-PEG2-CH2CO2tBu is a PEG (polyethylene glycol) linker that features a bromide group and a t-butyl protected carboxyl group. This molecule is designed to enhance solubility in aqueous environments due to the hydrophilic nature of the PEG spacer. The presence of the bromide group makes it an excellent candidate for nucleophilic substitution reactions, while the t-butyl protected carboxyl group can be selectively deprotected under acidic conditions, allowing for further functionalization and reaction with other molecules.
1807518-63-3
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Basic information
- Product Name: Bromo-PEG2-CH2CO2tBu
- Synonyms: Bromo-PEG2-CH2CO2tBu;Bromo-PEG2-CH2COOtBu;t-butyl acetate-PEG2-bromiade;Br-PEG2-CH2COOtBu
- CAS NO:1807518-63-3
- Molecular Formula: C10H19BrO4
- Molecular Weight: 283.15946
- EINECS: N/A
- Product Categories: N/A
- Mol File: 1807518-63-3.mol
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: /
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: N/A
- CAS DataBase Reference: Bromo-PEG2-CH2CO2tBu(CAS DataBase Reference)
- NIST Chemistry Reference: Bromo-PEG2-CH2CO2tBu(1807518-63-3)
- EPA Substance Registry System: Bromo-PEG2-CH2CO2tBu(1807518-63-3)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 1807518-63-3(Hazardous Substances Data)
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1807518-63-3 Usage
Uses
Used in Bioconjugation and Drug Synthesis:Bromo-PEG2-CH2CO2tBu is used as a bioconjugation agent for the attachment of various biomolecules, such as proteins, peptides, and other therapeutic agents. The bromide group facilitates the coupling process through nucleophilic substitution, while the PEG spacer provides increased solubility and stability to the final product.
Used in Drug Delivery Systems:
In the pharmaceutical industry, Bromo-PEG2-CH2CO2tBu is used as a component in the design of drug delivery systems. The PEG linker can be used to improve the solubility and bioavailability of drugs, while the t-butyl protected carboxyl group allows for the controlled release of the drug under specific conditions, such as in response to pH changes in the body.
Used in Chemical Synthesis:
Bromo-PEG2-CH2CO2tBu is also used as an intermediate in the synthesis of various chemical compounds, particularly those requiring a PEGylated structure. The versatility of the molecule, with its reactive bromide group and protected carboxyl group, makes it a valuable building block for creating a wide range of PEGylated products with diverse applications.
Used in Material Science:
In the field of material science, Bromo-PEG2-CH2CO2tBu can be used as a component in the development of novel materials with enhanced properties. The PEG linker can improve the hydrophilicity and biocompatibility of these materials, while the reactive bromide group and t-butyl protected carboxyl group allow for further modification and functionalization to tailor the material's properties for specific applications.
Check Digit Verification of cas no
The CAS Registry Mumber 1807518-63-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,8,0,7,5,1 and 8 respectively; the second part has 2 digits, 6 and 3 respectively.Calculate Digit Verification of CAS Registry Number 1807518-63:
(9*1)+(8*8)+(7*0)+(6*7)+(5*5)+(4*1)+(3*8)+(2*6)+(1*3)=183
183 % 10 = 3
So 1807518-63-3 is a valid CAS Registry Number.
1807518-63-3Upstream product
1807518-63-3Downstream Products
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Bromo-PEG2-CH2CO2tBu
